Results 61 to 70 of about 2,557,779 (357)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Persona

open access: yes, 2018
This chapter asks what room is there for stand-up comedy as social critique in a ‘post-abjection’ society. In a society where a New Left politics is normative, ‘common sense’, where does this leave radical critique for stand-up comedians? If New Left ideals are mainstream ‘political sense’, how do comedians face up to the obligations of New Left ...
openaire   +3 more sources

Defining Personas of People Living with Chronic Pain: An Ethnographic Research Study

open access: yesJournal of Pain Research, 2023
Melissa Cullens,1 Cyan James,1 Meran Liu,1 Amaresh Vydyanathan,2– 4 Naum Shaparin,3– 5 Michael Schatman,6,7 Jacob Hascalovici2,3,5,8 1Clearing Relief Labs Inc., New York City, NY, USA; 2Relief Medical Group P.A, New York City, NY, USA; 3Department of ...
Cullens M   +6 more
doaj  

An Enriched Customer Journey Map: How to Construct and Visualize a Global Portrait of Both Lived and Perceived Users’ Experiences?

open access: yesDesigns, 2020
Design is about understanding the system and its users. Although User Experience (UX) research methodologies aim to explain the benefits of a holistic measurement approach including explicit (e.g., self-reported) and implicit (e.g., automatic and ...
Juliana Alvarez   +5 more
doaj   +1 more source

Co-designing smart home technology with people with dementia or Parkinson's disease [PDF]

open access: yes, 2018
Involving users is crucial to designing technology successfully, especially for vulnerable users in health and social care, yet detailed descriptions and critical reflections on the co-design process, techniques and methods are rare.
Bourazeri, A., Stumpf, S.
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

El patrimonio

open access: yesEstudios de Derecho, 1960
El patrimonio.
Lucrecio Jaramillo vélez
doaj  

“yellow crowfoot in the pond,/not lotus, not lily”: Mapping the River, Mapping Voices [PDF]

open access: yes, 2016
This paper examines the prosody of Chin’s eponymous poem, The Phoenix Gone, The Terrace Empty, through an eco-critical lens. While it does not dismiss the hybrid cultural influences of the poem, it focuses on the ways the non-human agents, or the ...
Rader, Pamela J.
core   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Las leyes fundamentales de la estupidez humana

open access: yesCuadernos de Economía, 1996
La humanidad se encuentra -y sobre esto el acuerdo es unánime- en un estado deplorable. Ahora bien, no se trata de ninguna novedad. Si uno se atreve a mirar hacia atrás, se da cuenta de que siempre ha estado en una situación deplorable.
Cipolla Carlo M.
doaj  

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