Results 51 to 60 of about 7,912 (253)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
ENERGIES AND PERSONHOOD: A CHRISTOLOGICAL PERSPECTIVE ON HUMAN IDENTITY
The assertion that Christ is truly and fully human supports using Christology as a starting point to frame discussions surrounding humanity. This article focuses on the Christological distinction between personhood and nature that is made in the ...
doaj +2 more sources
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
This paper examines the evolution of legal personhood and explores whether historical precedents—from corporate personhood to environmental legal recognition—can inform frameworks for governing artificial intelligence (AI). By tracing the development of
Joffrey Baeyaert
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
Lecture One: Rediscovering Darwin for theology – Rethinking human personhood
In a series of three articles, presented at the Goshen Annual Conference on Science and Religion in 2015, with the theme ‘Interdisciplinary Theology and the Archeology of Personhood’, J.
J. Wentzel van Huyssteen
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Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
NATIONAL DIMENSIONS OF PERSONHOOD AMONG OLDER PEOPLE IN POLAND
Older people in Poland are often discriminated against in both practice and imagination, thus threatening their very status as moral persons.
Jessica C. ROBBINS-RUSZKOWSKI
doaj

