Results 121 to 130 of about 910,073 (334)

Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Phenoconversion, a genotype‐phenotype mismatch, challenges a successful implementation of personalized medicine. The aim of this study was to detect and determine phenoconversion using the solanidine metabolites 3,4‐seco‐solanidine‐3,4‐dioic acid (SSDA) and 4‐OH‐solanidine as diet‐derived cytochrome P450 2D6 (CYP2D6) biomarkers in a ...
Jens Andreas Sarömba, Julian Peter Müller, Jolanta Tupiec, Anjali Roeth, Berkan Kurt, Florian Kahles, Thea Laurentius, Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Co‐producing an inclusive‐care model for young people transitioning from adolescent eating disorder services to adult care: A qualitative study protocol for Transition for Eating Disorder Youth intervention

European Eating Disorders Review, EarlyView., 2023
Abstract Eating disorders (EDs) present a chronic issue to child paediatric mental health services due to their high mortality and relapse rates. The transition from Child and Adolescent Mental Health Services to Adult Mental Health Services is a particularly high‐risk period for young people with EDs given their high vulnerability to change, which can
Maria Livanou, Anya Heneghan, Elli Bouliou, Grace Hill, Katharine Mills, Sophie Naylor Roll, Zara Smalley, Jun Teh, Janet Treasure   +8 more
wiley   +1 more source

Evaluation of the Frequency of Methicillin-Resistant Staphylococs Isolated from Nose of Nursing Personnel of Hajar Hospital of Shahrekord [PDF]

, 2013
Background and Objectives: Methicillin-resistant Staphylococcus strains, as one of the most important etiologic agents of nosocomial infections are of particular importance due to their ability to create potential cross-resistance to all beta-lactam ...
Kalhor, Hoorieh., Nafisi, Mohammad Reza., Validi, Majid.   +2 more
core   +1 more source

Safety and effectiveness of the anti‐amyloid monoclonal antibody (mAb) drug lecanemab for early Alzheimer's disease: The pharmacovigilance perspective

British Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1352-1360, May 2025.
Abstract The development of humanized IgG1 anti‐amyloid monoclonal antibodies, such as lecanemab, provides a promising novel treatment pathway with potential disease‐modifying effects for patients with early Alzheimer's disease (AD). Lecanemab, which gained marketing approval by the United States Food and Drug Administration (US FDA) in July 2023, has ...
Amy Bobbins, Miranda Davies, Elizabeth Lynn, Debabrata Roy, Alison Yeomans, Saad A. W. Shakir   +5 more
wiley   +1 more source

Flexibility in hospital building and application by means of standardized medical room types [PDF]

, 2014
This paper presents an approach to standardization of hospital rooms. As hospitals are becoming more complex, the need for quality assurance and validation increases as well.
Ankersmid, H.A.H.G., Bonnema, G.M., Kamp, P.G., Kooistra, R.L.   +3 more
core   +1 more source

Adverse events associated with monoclonal antibodies used for treatment of COVID‐19: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1306-1321, May 2025.
Aims This review aimed to synthesise the evidence related to the incidence of serious and non‐serious adverse events with the use of monoclonal antibodies (mAbs) among COVID‐19 patients. Methods Databases were searched from January 2020 to September 2023 for randomized clinical trials (RCTs) that used mAbs for the treatment of COVID‐19 regardless of ...
Htet Htet, Han You Kyung, Ismail Abdul Sattar Burud, Heethal Jaiprakash, Thiruselvi Subramaniam, Igor Iezhitsa, Renu Agarwal   +6 more
wiley   +1 more source

Implementation of mass pharmacogenetic testing: Dihydropyrimidine dehydrogenase testing prior to fluoropyrimidine treatment for patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Pharmacogenomics enables personalization of drug therapy improving effectiveness and/or safety. Dihydropyrimidine dehydrogenase [DPYD] testing prior to fluoropyrimidine chemotherapy was commissioned by NHS England in response to an update from the Medicines and Healthcare products Regulatory Agency.
Nisha Shaunak, Jessica Keen, Anna Kim, Munir Pirmohamed, William G. Newman, Paul J. Ross   +5 more
wiley   +1 more source

RETRACTED: Artificial intelligence for emergency medical care

Health Care Science, EarlyView., 2023
‘Applications of artificial intelligence in emergency medical service’. Abstract There is increasing research into the potential benefits of incorporating artificial intelligence (AI) and machine learning algorithms into emergency medical services. AI is finding new applications across a wide range of sectors, one of which is healthcare, where it is ...
Shivam Rajput, Pramod Kumar Sharma, Rishabha Malviya   +2 more
wiley   +1 more source

Beacon Light: November 1962 [PDF]

, 1962
Dorraine Tomczik was elected chair of the St. Cloud hospital personnel advisory committee Profile on Rita Bloch a surgical aide A reminder to all personnel to maintain clean working environments Nurses attended a patient care workshop at Iowa State ...
St. Cloud
core   +1 more source

Nosocomial Infections Pathogens Isolated from Hospital Personnel, Hospital Environment and Devices

Journal of Medical Bacteriology, 2018
Background:    Nosocomial infections has always been a major problem for health care and lead to increases in morbidity and mortality in hospitalized patients. The aim of this study was to determine the contamination of personnel and hospital environment
Reza Akbari, Mehdi Fattahi Bafghi, Hossain Fazeli   +2 more
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