Results 161 to 170 of about 5,838,612 (374)
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
Theory of Mind: A Review of Recent Empirical Results and Main Theoretical Explanations
Theory of Mind is the ability to attribute mental states to others. Until around 20 years ago most evidence pointed to Theory of Mind being a cognitively demanding skill that likely develops at around 4 years of age.
Edward W. Legg
doaj
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Perspective taking and transformational leadership: Working paper series--08-07 [PDF]
This exploratory study examined potential relationships between a supervisor's perspective taking within a given supervisor/subordinate dyad and assessments of that supervisor's leadership style.
Gregory, Brian T., Moates, K. Nathan
core
“Teposliro” and “Semuci” among Public Accountants: Do We Know, and Do We Care?
The purpose of this paper is to examine the attitude of public accountants in situations of ethical dilemmas in their professional activities. This paper examines the effect of ‘teposliro’ on ethical decision-making and seek to establish the prevalence ...
Sasongko Budisusetyo, Bambang Subroto
doaj
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
Social perspective-taking influences on metacognition
We often effortlessly take the perceptual perspective of others: we represent some aspect of the environment that others currently perceive. However, taking someone's perspective can interfere with one's perceptual processing: another person's gaze can spontaneously affect our ability to detect stimuli in a scene.
Battich, Lucas+2 more
openaire +2 more sources
The Slow Work of Democracy: Resisting Reductionist Views of Women and Children [PDF]
In her research article "State your defense!": Children negotiate analytic frames in the context of deliberative dialogue," Hauver offers important contributions to the field of elementary civic education that illuminate how young people apply various ...
Serriere, Stephanie C.
core +1 more source
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Spontaneous mindreading: a problem for the two-systems account [PDF]
According to the two-systems account of mindreading, our mature perspective-taking abilities are subserved by two distinct mindreading systems: a fast but inflexible, “implicit” system, and a flexible but slow “explicit” one.
Westra, Evan
core