Results 111 to 120 of about 536,582 (323)

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Complementary wave solutions for the long-short wave resonance model via the extended trial equation method and the generalized Kudryashov method

open access: yesOpen Physics, 2018
In this paper the nonlinear long-short (LS) wave resonance model is analyzed through a new perspective. We obtain the classification of exact solutions by making use of the complete discrimination system for the trial equation method and through the ...
Cimpoiasu Rodica, Pauna Alina Streche
doaj   +1 more source

Get Beyond Limits: From Colloidal Tectonics Concept to the Engineering of Eco-Friendly Catalytic Systems

open access: yesFrontiers in Chemistry, 2018
The interactions between two or more molecules or colloidal particles can be used to obtain a variety of self-assembled systems called supramolecules or supracolloids. There is a clear, but neglected, convergence between these two fields.
Loïc Leclercq
doaj   +1 more source

Proof of Blum's conjecture on hexagonal dungeons [PDF]

open access: yesarXiv, 2014
Matt Blum conjectured that the number of tilings of the Hexagonal Dungeon of sides $a,\ 2a,\ b,\ a,\ 2a,\ b$ (where $b\geq 2a$) is $13^{2a^2}14^{\lfloor\frac{a^2}{2}\rfloor}$ (J. Propp, New Perspectives in Geometric Combinatorics, Cambridge University Press, 1999).
arxiv  

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Introduction: New Perspectives on Swiss Graphic Design [PDF]

open access: yesDesign Issues, 2021
Fornari, Davide   +5 more
openaire   +3 more sources

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

Light-Field Imaging Toolkit

open access: yesSoftwareX, 2016
The Light-Field Imaging Toolkit (LFIT) is a collection of MATLAB functions designed to facilitate the rapid processing of raw light field images captured by a plenoptic camera.
Jeffrey Bolan   +3 more
doaj  

Teaching Post Keynesian Exchange Rate Theory [PDF]

open access: yes
The goal of this paper is to provide a model and method for those wishing to include the Post Keynesian perspective when teaching exchange rate theory. It begins by reviewing neoclassical approaches (purchasing power parity, the monetary model, and the ...
John Harvey
core  

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