Results 101 to 110 of about 1,338,740 (314)

A Forward–Backward–Forward Algorithm for Quasi-Variational Inequalities in the Moving Set Case

Mathematics
This paper addresses the challenge of solving quasi-variational inequalities (QVIs) by developing and analyzing a forward–backward–forward algorithm from a continuous and iterative perspective.
Nevena Mijajlović, Ajlan Zajmović, Milojica Jaćimović   +2 more
doaj   +1 more source

Off the Grid [PDF]

, 2017
Off the Grid explores the messy relationship between public and private perceptions of our urban spaces, especially the tensions created when lived experience runs up against the physical and conceptual networks of cities: street grids, construction tape,
Buffington, Matthew Owen
core   +2 more sources

IT Project Management from a Systems Thinking Perspective

, 2008
Purpose: We proposes a Systems Thinking approach to the study of IT project management and show how this approach helps project managers in controlling their projects. Systems Thinking is a holistic problem solving method in which system behaviour emerges from the interaction of system components. Design/methodology/approach: To illustrate our proposal,
van Eck, Pascal, Ponisio, Laura
openaire   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Pilot Design for Sparse Channel Estimation in Large-Scale MIMO-OFDM System

International Journal of Antennas and Propagation, 2016
The pilot design problem in large-scale multi-input-multioutput orthogonal frequency division multiplexing (MIMO-OFDM) system is investigated from the perspective of compressed sensing (CS).
Chao Xu, Jianhua Zhang, Mengmeng Liu, Changchuan Yin   +3 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Project Strategy and Stakeholder Theory: A System Dynamics Perspective

International Journal of Intelligent Systems and Applications in Engineering
Research in the area of project strategy has been limited in project management research. In this paper we present the perspectives of project strategy available in literature. Then we present an approach towards an integrated view of project strategy from the viewpoint of stakeholder theory.
Sarojkant Singh, Mridanish Jha
openaire   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A multispectral study of an extratropical cyclone with Nimbus 3 medium resolution infrared radiometer data [PDF]

Four registered channels (0.2 to 4, 6.5 to 7, 10 to 11, and 20 to 23 microns) of the Nimbus 3 Medium Resolution Infrared Radiometer (MRIR) were used to study 24-hr changes in the structure of an extratropical cyclone during a 6-day period in May 1969 ...
Holub, R., Shenk, W. E.
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source