Results 131 to 140 of about 8,782,298 (371)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Folktales of International Justice [PDF]

open access: yes, 2004
When Laura Dickinson asked me to participate on this panel, she very nicely said that she hoped I could bring a different perspective to the discussion. I thought I knew what she meant.
Luban, David
core   +1 more source

Liquid retail:cultural perspectives on marketplace transformation [PDF]

open access: yes, 2018
Inspired by Bauman’s notion of ‘liquidity’, we problematize the socio-cultural dynamics taking place in contemporary retail. The notion of liquid retail enables reserachers to untangle marketplace transformation and to highlight developments centred ...
Bajde, Domen   +2 more
core   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

The role of perspective-talking in the understanding of cooperation and relationship marketing [PDF]

open access: yes, 2009
Relationship marketing has established itself as one of the main pursuits in marketing. Various viewpoints have been proposed seeking to explicate relationship marketing.
Academy of Marketing Conference : Putting Marketing in its Place   +4 more
core  

Creativity through Connectedness: The Role of Closeness and Perspective Taking in Group Creativity

open access: yesCreativity Research Journal, 2018
Achievements in various fields of creativity are resulting more and more from collaborative teams. This research investigated the role of interpersonal process variables, namely closeness and perspective taking in group creativity, with a 2 by 2 ...
Pınar Oztop   +2 more
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

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