Results 191 to 200 of about 3,419 (230)
Hydrogen Sulfide Signaling in Neurodegenerative Movement Disorders. [PDF]
Handb Exp PharmacolPieper AA, Paul BD.
europepmc +1 more source
Mechanism of Intracellular Elemental Sulfur Oxidation in Beggiatoa leptomitoformis, Where Persulfide Dioxygenase Plays a Key Role. [PDF]
Int J Mol SciRudenko TS +8 more
europepmc +1 more source
Persulfide Biosynthesis Conserved Evolutionarily in All Organisms
Antioxidants and Redox Signaling, 2023 Significance: Persulfides/polysulfides are sulfur-catenated molecular species ( i.e. , R-S n -R′, n > 2; R-S n
Seiryo Ogata +2 more
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Methods in sulfide and persulfide research
Nitric Oxide, 2021Sulfides and persulfides/polysulfides (R-Sn-R', n > 2; R-Sn-H, n > 1) are endogenously produced metabolites that are abundant in mammalian and human cells and tissues. The most typical persulfides that are widely distributed among different organisms include various reactive persulfides-low-molecular-weight thiol compounds such as cysteine ...
Tsuyoshi Takata +9 more
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Molecular Plant, 2021
Post-translational modifications (PTMs), including phosphorylation and persulfidation, regulate the activity of SNF1-RELATED PROTEIN KINASE2.6 (SnRK2.6). Here, we report how persulfidations and phosphorylations of SnRK2.6 influence each other. The persulfidation of cysteine C131/C137 alters SnRK2.6 structure and brings the serine S175 residue closer to
Sisi Chen +11 more
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Post-translational modifications (PTMs), including phosphorylation and persulfidation, regulate the activity of SNF1-RELATED PROTEIN KINASE2.6 (SnRK2.6). Here, we report how persulfidations and phosphorylations of SnRK2.6 influence each other. The persulfidation of cysteine C131/C137 alters SnRK2.6 structure and brings the serine S175 residue closer to
Sisi Chen +11 more
openaire +2 more sources
Mechanism-based inhibition of human persulfide dioxygenase by γ-glutamyl-homocysteinyl-glycine [PDF]
Journal of Biological Chemistry, 2018 Ömer Kabil +2 more
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Acidity and nucleophilic reactivity of persulfides
The FASEB Journal, 2022Persulfides(RSSH/RSS ‐ ) are chemical compounds related to thiols (RSH) and hydrogen sulfide (H 2 S). They participate in sulfur trafficking and processing, and are proposed to be transducers of the signaling effects of H 2
Dayana Benchoam +3 more
openaire +1 more source
Journal of the American Chemical Society, 2017
A general strategy of delivering hydrogen persulfide (H2S2) is described herein. Esterase- and phosphatase-sensitive H2S2 prodrugs with tunable release rates have been synthesized. Their utility is validated in examining protein S-persulfidation. With this unique approach of directly delivering H2S2, our findings reaffirmed that S-persulfidation leads ...
Bingchen Yu +9 more
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A general strategy of delivering hydrogen persulfide (H2S2) is described herein. Esterase- and phosphatase-sensitive H2S2 prodrugs with tunable release rates have been synthesized. Their utility is validated in examining protein S-persulfidation. With this unique approach of directly delivering H2S2, our findings reaffirmed that S-persulfidation leads ...
Bingchen Yu +9 more
openaire +2 more sources
Targeted Delivery of Persulfides to the Gut: Effects on the Microbiome
Angewandte Chemie, 2021AbstractPersulfides (R−SSH) have been hypothesized as potent redox modulators and signaling compounds. Reported herein is the synthesis, characterization, and in vivo evaluation of a persulfide donor that releases N‐acetyl cysteine persulfide (NAC‐SSH) in response to the prokaryote‐specific enzyme nitroreductase.
Kearsley M. Dillon +8 more
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