Results 71 to 80 of about 1,196,383 (294)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A proposed methodology for trip recovery training without a specialized treadmill

open access: yesFrontiers in Sports and Active Living, 2022
Falls are the leading cause of accidental injuries among adults aged 65 years and older. Perturbation-based balance training is a novel exercise-based fall prevention intervention that has shown promise in reducing falls. Trip recovery training is a form
Youngjae Lee   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Analysis of a multiphase free boundary problem [PDF]

open access: yesOpuscula Mathematica
In this paper, we investigate a free boundary problem relevant in several applications, such as tumor growth models. Our problem is expressed as an elliptic equation involving discontinuous nonlinearities in a specified domain with a moving boundary.
Ahlem Abdelouahab, Sabri Bensid
doaj   +1 more source

The non-adiabatic pressure in general scalar field systems

open access: yes, 2009
We discuss the non-adiabatic or entropy perturbation, which controls the evolution of the curvature perturbation in the uniform density gauge, for a scalar field system minimally coupled to gravity with non-canonical action.
Adam J. Christopherson   +27 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Inflationary Tensor Perturbation in Eddington-inspired Born-Infeld gravity

open access: yes, 2014
We investigate the tensor perturbation in the inflation model driven by a massive-scalar field in Eddington-inspired Born-Infeld gravity. For short wave-length modes, the perturbation feature is very similar to that of the usual chaotic inflation.
Cho, Inyong, Kim, Hyeong-Chan
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Energy diffusion in strongly driven quantum chaotic systems

open access: yes, 2005
The energy evolution of a quantum chaotic system under the perturbation that harmonically depends on time is studied for the case of large perturbation, in which the rate of transition calculated from the Fermi golden rule exceeds the frequency of ...
A. Allen   +20 more
core   +1 more source

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