Results 111 to 120 of about 13,036,763 (283)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Research on Material Temperature Perturbation Methods Based on RMC

Yuanzineng kexue jishu
A second-order material temperature perturbation algorithm applicable to the full-energy range of non-thermalized isotopes based on the RMC code was developed, and a corresponding method for solving temperature derivatives of cross-section was proposed ...
WANG Wu1, WANG Kan2, TONG Pu1, GUO Juanjuan1
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Comparative Analysis of Perturbation Characteristics Between LBGM and ETKF Initial Perturbation Methods in Convection-Permitting Ensemble Forecasts

Atmosphere
This study investigates an extreme squall line event that occurred in northern Jiangxi Province, China on 30–31 March 2024. Based on the WRF model, convection-permitting ensemble forecast experiments were conducted using two distinct initial perturbation
Jiajun Li, Chaohui Chen, Xiong Chen, Hongrang He, Yongqiang Jiang, Yanzhen Kang   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Secular Resonances in Planet-hosting Binary Stars. I. General Theory

The Astronomical Journal
Motivated by the diversity of circumstellar planets in binary stars and the strong effects of the secular resonances of Jupiter and Saturn on the formation and architecture of the inner solar system, we have launched an expansive project on studying the ...
Nader Haghighipour, Michael Andrew
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Solving the Multi-Country Real Business Cycle Model Using Ergodic Set Methods [PDF]

We use the stochastic simulation algorithm, described in Judd, Maliar and Maliar (2009), and the cluster-grid algorithm, developed in Judd, Maliar and Maliar (2010a), to solve a collection of multi-country real business cycle models.
Lilia Maliar, Kenneth L. Judd, Serguei Maliar   +2 more
core  

Perturbation Methods for Acoustic Systems with Interval Parameters

Archives of Acoustics, 2008
The aim of the paper is to present a new algebraic system with strictly defined new interval numbers and specifically defined addition and multiplication operations.
Jerzy SKRZYPCZYK
doaj