Results 101 to 110 of about 233,327 (304)

Nontrivial Solution for the Fractional p-Laplacian Equations via Perturbation Methods

Advances in Mathematical Physics, 2017
We study the existence of nontrivial solution of the following equation without compactness: (-Δ)pαu+up-2u=f(x,u),  x∈RN, where N,p≥2,  α∈(0,1),  (-Δ)pα is the fractional p-Laplacian, and the subcritical p-superlinear term f∈C(RN×R) is 1-periodic in xi ...
Huxiao Luo, Shengjun Li, Xianhua Tang
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Dynamical Structures Associated with High-Order and Secondary Resonances in the Spin–Orbit Problem

The Astronomical Journal
In our solar system, spin–orbit resonances are common under Sun–planet, planet–satellite, and binary asteroid configurations. In this work, high-order and secondary spin–orbit resonances are investigated by taking numerical and analytical approaches ...
Hanlun Lei
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Small-scale Dynamo with Nonzero Correlation Time

The Astrophysical Journal
The small-scale dynamo is typically studied by assuming that the correlation time of the velocity field is zero. Some authors have used a smooth renovating flow model to study how the properties of the dynamo are affected by the correlation time being ...
Kishore Gopalakrishnan, Nishant K Singh
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Secular Dynamics of Compact Three-planet Systems

The Astrophysical Journal
The secular Laplace–Lagrange orbital solution, decomposing eccentricities into a set of uniformly precessing eigenmodes, is a classical result that is typically solved numerically.
Qing Yang, Daniel Tamayo
doaj   +1 more source

Sound Attenuation in Elliptic Mufflers Using a Regular Perturbation Method

, 2012
The study of sound attenuation in an elliptical chamber involves the solution of the Helmholtz equation in elliptic coordinate systems. The Eigen solutions for such problems involve the Mathieu and the modified Mathieu functions.
Jacobi, Anthony M., Banerjee, Subhabrata
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source