Results 81 to 90 of about 233,327 (304)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Approximate solution to a hybrid model with stochastic volatility: a singular-perturbation strategy
, 2009 We study a hybrid model of Schobel-Zhu-Hull-White-type from a singular-perturbation-analysis perspective. The merit of the paper is twofold: On one hand, we find boundary conditions for the deterministic non-linear degenerate parabolic partial ...
Hendriks, H, Fatima, T, Grzelak, L
core
Perturbation Analysis for Robust Damage Detection with Application to Multifunctional Aircraft Structures [PDF]
, 2014 The most widely known form of multifunctional aircraft structure is smart structures for structural health monitoring (SHM). The aim is to provide automated systems whose purposes are to identify and to characterize possible damage within structures by ...
HAJRYA, Rafik, MECHBAL, Nazih
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Aspects of self-adaptive control using parameter perturbation techniques [PDF]
This thesis is concerned with the performance of a method of simultaneous identification and optimization of a control system, employing a parameter perturbation technique.
Pawley, Anthony John Robert
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
RS-invariant resummations of QCD perturbation theory [PDF]
, 1997 We propose a renormalon-inspired resummation of QCD perturbation theory based on approximating the renormalization scheme (RS) invariant effective charge (EC) beta- function coefficients by the portion containing the highest power of b = (11N'-2N(_f))/6,
Tonge, D.G., Tonge, Darrell Graham
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Neuromuscular organization during balance-correcting responses induced with platform-translation and upper body cable-pull perturbation methods. [PDF]
Heliyon, 2023 Verniba D, Di Bacco VE, Gage WH.
europepmc +1 more source
Bounded perturbation resilience of extragradient-type methods and their applications
Journal of Inequalities and Applications, 2017 In this paper we study the bounded perturbation resilience of the extragradient and the subgradient extragradient methods for solving a variational inequality (VI) problem in real Hilbert spaces.
Q-L Dong, A Gibali, D Jiang, Y Tang
doaj +1 more source