Results 71 to 80 of about 753,055 (286)

Nonlinear systems approach to control system design [PDF]

, 1984
Consider some of the control system design methods for plants with nonlinear dynamics. If the nonlinearity is weak relative to the size of the operating region, then the linear methods apply directly.
Meyer, G.
core   +1 more source

Analytic approximations, perturbation theory, effective field theory methods and their applications

, 2014
We summarize the parallel session B4: 'Analytic approximations, perturbation theory effective field theory methods and their applications' and the joint session B2/B4: 'Approximate solutions to Einstein equations: Methods and Applications', of the GR20 &
Cardoso, Vitor, Porto, Rafael A.
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Electromechanical Model and Transient Behaviors of Power Systems

Energies
A large-scale power system is often represented by a set of differential-algebraic equations, so-called electromechanical models. In this paper, it is shown that these models can have several analytical properties, which can be exploited to help the ...
Xueting Cheng, Deqiang Gan
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Variational methods and degenerate perturbation theory [PDF]

Variational methods and degenerate perturbation ...
Epstein, S. T.
core   +1 more source

Renormalization Group Theory for Global Asymptotic Analysis

, 1994
We show with several examples that renormalization group (RG) theory can be used to understand singular and reductive perturbation methods in a unified fashion.
A. C. Newell, C. M. Bender, E. C. G. Stueckelberg, E. J. Hinch, G. I. Barenblatt, G. Paquette, J. Bricmont, J. D. Crawford, J. Kevorkian, J. Swift, J. Zinn-Justin, L. Y. Chen, Lin Yuan Chen, M. C. Cross, M. Gell-Mann, N. D. Goldenfeld, N. Goldenfeld, N. Goldenfeld, Nigel Goldenfeld, S. L. Woodruff, T. Taniuti, Y. Kuramoto, Y. Oono   +22 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source