Results 51 to 60 of about 13,036,763 (283)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Class-Level Logit Perturbation [PDF]
Features, logits, and labels are the three primary data when a sample passes through a deep neural network (DNN). Feature perturbation and label perturbation receive increasing attention in recent years. They have been proven to be useful in various deep
Wu, Ou +3 more
core +1 more source
Accurate Landmark Localization for Medical Images Using Perturbations
Applied Sciences, 2021 Recently, various studies have been proposed to learn the rich representations of images during deep learning. In particular, the perturbation method is a simple way to learn rich representations that has shown significant success.
Junhyeok Kang, Kanghan Oh, Il-Seok Oh
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
AxiomsThis paper examines the stability behavior of the nonlinear dynamical motion of a vibrating cart with two degrees of freedom (DOFs). Lagrange’s equations are employed to establish the mechanical regulating system of the examined motion.
Muneerah AL Nuwairan +2 more
doaj +1 more source
The exact solutions of nonlinear problems by Homotopy Analysis Method (HAM) [PDF]
Computational Ecology and Software, 2016 The present paper presents the comparison of analytical techniques. We establish the existence of the phenomena of the noise terms in the perturbation series solution and find the exact solution of the nonlinear problems.
Hafiz Abdul Wahab +2 more
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Static Perturbation Analysis of Inclined Shallow Elastic Cables under general 3D-loads
Curved and Layered Structures, 2016 Inclined, shallow, elastic cables under static 3D loads, arbitrarily distributed, are studied. Cables having natural length both larger or smaller than the distance between the supports (i.e.
Luongo Angelo, Zulli Daniele
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Variational methods and degenerate perturbation theory [PDF]
, 1965 Variational methods and degenerate perturbation ...
Epstein, S. T.
core