Results 51 to 60 of about 160,382 (249)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Well-posedness and stability analysis of hybrid feedback systems using Shkalikov's theory [PDF]
Opuscula Mathematica, 2006 The modern method of analysis of the distributed parameter systems relies on the transformation of the dynamical model to an abstract differential equation on an appropriately chosen Banach or, if possible, Hilbert space.
Piotr Grabowski
doaj
Small denominators, frequency operators, and Lie transforms for nearly integrable quantum spin systems [PDF]
, 1996 Based on the previously proposed notions of action operators and of quantum integrability, frequency operators are introduced in a fully quantum-mechanical setting.
A. J. Lichtenberg +29 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2017 Inspired by the idea of mimicking the measurement on a quantum system through a decoherence process to target specific eigenstates based on Born's law, i.e.
Furtmaier, Oliver, Mendoza, Miller
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Conformal Current Algebra in Two Dimensions
, 2009 We construct a non-chiral current algebra in two dimensions consistent with conformal invariance. We show that the conformal current algebra is realized in non-linear sigma-models on supergroup manifolds with vanishing dual Coxeter number, with or ...
A. Giveon +12 more
core +2 more sources
Theory of invariants-based formulation of ${\bf k}\cdot{\bf p}$ Hamiltonians with application to strained zinc-blende crystals [PDF]
, 2017 Group theoretical methods and ${\bf k}\cdot{\bf p}$ theory are combined to determine spin-dependent contributions to the effective conduction band Hamiltonian.
Eckern, Ulrich +2 more
core +2 more sources
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Hadamard’s Variational Formula for Simple Eigenvalues
AppliedMathHere, we study Hadamard’s variational formula for simple eigenvalues under dynamical and conformal deformations. Particularly, harmonic convexity of the first eigenvalue of the Laplacian under the mixed boundary condition is established for a two ...
Takashi Suzuki, Takuya Tsuchiya
doaj +1 more source