Results 91 to 100 of about 146,306 (301)

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, EarlyView.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Highlights of the 14th International Bordetella Symposium

mSphere
Pertussis, or whooping cough, is a highly contagious and acute respiratory illness caused primarily by the gram-negative coccobacillus Bordetella pertussis.
Kevin Munoz Navarrete, Kathryn M. Edwards, Kingston H. G. Mills, Jana Kamanová, María Eugenia Rodriguez, Andrew Gorringe, Andrew Preston, Beate Kampmann, Monica C. Gestal, Eric T. Harvill, Purnima Dubey, Dimitri A. Diavatopoulos, Seema Mattoo, Karen M. Scanlon, Camille Locht, Peter Sebo   +15 more
doaj   +1 more source

Burden of Pertussis in Individuals with a Diagnosis of Asthma: A Retrospective Database Study in England

Journal of Asthma and Allergy, 2022
Amit Bhavsar,1 Emmanuel Aris,2 Lauriane Harrington,3 Jason C Simeone,4 Anna Ramond,5 Dimitra Lambrelli,5 Alberto Papi,6 Louis-Philippe Boulet,7 Kinga Meszaros,8 Nicolas Jamet,8 Yan Sergerie,3 Piyali Mukherjee3 1Europe Medical Affairs, GSK, Wavre, Belgium;
Bhavsar A, Aris E, Harrington L, Simeone JC, Ramond A, Lambrelli D, Papi A, Boulet LP, Meszaros K, Jamet N, Sergerie Y, Mukherjee P   +11 more
doaj  

Understanding the Epidemiology of Pertussis in Denmark

Acta Paediatrica, EarlyView.
Tine Dalby, Aoife Ronayne, Peter Henrik Andersen   +2 more
wiley   +1 more source

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

European Journal of Haematology, EarlyView.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot, Frederic Baleydier, Laure Pittet, Geraldine Blanchard‐Rohner   +3 more
wiley   +1 more source

SARS-CoV-2 coinfections among pertussis cases identified through the Enhanced Pertussis Surveillance system in the United States, January 2020-February 2023.

PLoS ONE
BackgroundBacterial and viral respiratory coinfections are common, but the prevalence of SARS-CoV-2 infections among pertussis cases has not been estimated.
Isha Berry, Matthew Cole, Benjamin Silk, Fiona P Havers, Erin Youngkin, Adam Misiorski, Samantha Sefton, Yeng Vang, Emma Stanislawski, Suzanne McGuire, Noel Silhan, Tami H Skoff, Amy B Rubis   +12 more
doaj   +1 more source

Genetically detoxified pertussis toxin induces superior antigen specific CD4 T cell responses compared to chemically detoxified pertussis toxin

Human Vaccines & Immunotherapeutics, 2019
Pertussis is resurgent worldwide. Currently available acellular pertussis vaccines contain chemically detoxified pertussis toxin (PTc); a highly immunogenic genetically detoxified pertussis toxin (PTg) vaccine has been off the market for over a decade ...
Naveen Surendran, Michael Pichichero
doaj   +1 more source

Association of Pertussis Toxin with Severe Pertussis Disease

Toxins, 2019
Pertussis, caused by respiratory tract infection with the bacterial pathogen Bordetella pertussis, has long been considered to be a toxin-mediated disease. Bacteria adhere and multiply extracellularly in the airways and release several toxins, which have
Karen Scanlon, Ciaran Skerry, Nicholas Carbonetti   +2 more
doaj   +1 more source

Exocytosis from permeabilized bovine adrenal chromaffin cells is differently modulated by guanosine 5'-[gamma-thio]triphosphate and guanosine 5'-[beta gamma-imido]triphosphate [PDF]

, 1992
1. In bovine adrenal chromaffin cells made permeable either to molecules less than or equal to 3 kDa with alphatoxin or to proteins less than or equal to 150 kDa with streptolysin O, the GTP analogues guanosine 5'-[beta gamma-imido]triphosphate (p[NH]ppG)
Ahnert-Hilger, G., Gratzl, Manfred, Rosenthal, W., Spicher, K., Stecher, B., Wegenhorst, U.   +5 more
core  

Bordetella pertussis

Microbiology Spectrum, 2016
ABSTRACTPertussis is a highly infectious vaccine-preventable cough illness that continues to be a significant source of morbidity and mortality around the world. The majority of human illness is caused byBordetella pertussis, and some is caused byBordetella parapertussis.Bordetellais a Gram-negative, pleomorphic, aerobic coccobacillus.
Delma J, Nieves, Ulrich, Heininger
openaire   +2 more sources