Results 121 to 130 of about 146,306 (301)

Comparative genomic profiling of Dutch clinical Bordetella pertussis isolates using DNA microarrays: Identification of genes absent from epidemic strains [PDF]

open access: gold, 2008
Audrey J. King   +9 more
openalex   +1 more source

The Effect of Physical Disability on Employment

open access: yesScottish Journal of Political Economy, Volume 73, Issue 1, February 2026.
ABSTRACT The relationship between physical disability and employment is explored using microdata for older working‐age women in the 2016 Irish Census of Population and historical data on the incidence of infectious diseases. Two‐stage least squares and recursive bivariate probit estimations are employed to account for the potential endogeneity of ...
Irene Mosca
wiley   +1 more source

Characterization ofBordetella pertussisclinical isolates that do not express the tracheal colonization factor [PDF]

open access: bronze, 2007
Marjolein van Gent   +5 more
openalex   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles   +3 more
wiley   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

open access: yesAdvanced Functional Materials, Volume 36, Issue 5, 15 January 2026.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang   +9 more
wiley   +1 more source

CYP4X1/sEH‐Dependent Endocannabinoid Metabolism Drives Fibroblast‐Mediated Immunosuppression to Limit Immunotherapy in Colon Cancer

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
A proposed mechanism to explain the role of CYP4X1/sEH‐14,15‐EET‐EA system in colon cancer immune escape. 14,15‐EET‐EA, 14,15‐epoxyeicosatrienoic acid‐ethanolamide; sEH, soluble epoxide hydrolase; CYP4X1, cytochrome P450 4X1; GPR119, G‐protein coupled receptor 119; EGFR, epidermal growth factor receptor; Gs, Gαs subunit; cAMP, cyclic adenosine ...
Min Mo   +10 more
wiley   +1 more source

Evaluating the Relationship Between the Introduction of the Acellular Pertussis Vaccine and Whooping Cough Resurgence in the United States

open access: yesVaccines
Background/Objectives: The whole cell pertussis vaccine was introduced in the United States in the 1940s and switched to the acellular pertussis vaccine partially in 1992 and completely in 1997. This study examines the relationship between the resurgence
Jeegan Parikh   +2 more
doaj   +1 more source

Prevention of pertussis: An unresolved problem

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis. However, after the introduction of the whole-cell pertussis vaccine (wP), the annual incidence rates of the disease progressively declined.
Susanna Esposito, Nicola Principi
doaj   +1 more source

Vibromixers as an Alternative to Stirred Tanks: Design, Performance Characteristics, and Applications

open access: yesChemical Engineering &Technology, Volume 49, Issue 1, January 2026.
This review presents the state‐of‐the‐art knowledge on vibromixers, which are alternative mixing systems to conventional rotating agitators and mostly used in the biotechnology sector. It critically surveys the working principles of different vibromixer types and their operating conditions, the designs and key geometrical parameters, hydrodynamics and ...
Muhammad Muhammad Gimba   +2 more
wiley   +1 more source

Elevated CHI3L1 as a Potential Biomarker of Cognitive Dysfunction in Anti‐NMDAR Encephalitis: Evidence From Clinical Results and Mice Model

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Astrocyte‐derived CHI3L1 is elevated in both a mouse model and pediatric patients with anti‐NMDAR encephalitis, coinciding with impaired hippocampal neurogenesis and cognitive deficits. CHI3L1 may serve as a potential biomarker for long‐term cognitive dysfunction in anti‐NMDAR encephalitis. ABSTRACT Background Anti‐N‐methyl‐D‐aspartate receptor (NMDAR)
Yuhang Li   +11 more
wiley   +1 more source

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