Results 131 to 140 of about 125,197 (248)

Geographic and Temporal Variations in Immunization Coverage in Nepal: An Ecological Time‐Trend Analysis

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Immunization remains a vital public health intervention in Nepal, yet significant disparities persist. This study evaluates the performance of Nepal's national immunization program by analyzing district‐level vaccination coverage and dropout rates from 2009 to 2022 to identify trends and disparities across different routine ...
Kritika Rana   +6 more
wiley   +1 more source

miR‐146a/b‐5p‐IRAK1‐NF‐κB Axis Regulates Unexplained Recurrent Spontaneous Abortion

open access: yesJournal of Molecular Recognition, Volume 39, Issue 3, May 2026.
ABSTRACT Unexplained recurrent spontaneous abortion (URSA) remains a prevalent obstetric issue, the underlying causes of which are still not fully understood. MicroRNAs (miRNAs) have the potential to influence URSA through their regulation of gene expression.
Fengping He   +7 more
wiley   +1 more source

EPI Update, August 31, 2012 [PDF]

open access: yes, 2012
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

High‐Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor

open access: yesMedComm, Volume 7, Issue 5, May 2026.
We conducted a high‐throughput screen of 2747 FDA‐approved drugs to identify inhibitors of pyroptosis. We found that CeeNU significantly repressed NLRP3‐dependent IL‐1β release and GSDMD pore‐forming complex. We identified that the arginine 335 amino acid of the NACHT domain of NLRP3 is the critical point for human NLRP3 and CeeNU interaction and ...
Sen‐Lin Ji   +11 more
wiley   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2219-2235, May 2026.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind   +6 more
wiley   +1 more source

A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2360-2375, May 2026.
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto   +12 more
wiley   +1 more source

Vaccine Risk Communication: Lessons from Risk Perception, Decision Making and Environmental Risk Communication Research [PDF]

open access: yes, 1997
Dr. Bostrom reviews the rich variety of empirical findings available to guide risk communication and demonstrates how it can contribute to vaccine risk and safety ...
Bostrom, Ann
core   +2 more sources

Hepatitis B Virus, Pneumococcal, Diphtheria, and Tetanus Vaccination Responses in Compensated Cirrhosis

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims Cirrhosis favours infections that can lead to liver decompensation and death. Some of these infections can be prevented by vaccination. This study aimed to evaluate the immune response after HBV, pneumococcal, diphtheria, and tetanus vaccination in cirrhotic patients.
Vincent Haghnejad   +10 more
wiley   +1 more source

Analysis of pertussis surveillance data (2022–2023) in a district of Beijing

open access: yesBMC Infectious Diseases
Introduction This study describes the epidemiological and drug resistance characteristics of Bordetella pertussis (B. pertussis) isolated from chronic/protracted cough patients in Beijing, China.
Yuanyuan Wang   +12 more
doaj   +1 more source

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