Results 61 to 70 of about 600,713 (168)

Antimicrobial susceptibilities of Bordetella species isolated in a Multicenter Pertussis Surveillance Project [PDF]

Antimicrobial Agents and Chemotherapy, 1988
MICs for 90% (MIC90s) of 75 Bordetella pertussis strains for amoxicillin, erythromycin, rifampin, and sulfamethoxazole-trimethoprim were 1, less than or equal to 0.12, 1, and 4 micrograms/ml, respectively. Susceptibility rates were all greater than or equal to 93%. Only 17% of the strains were susceptible to tetracycline.
T A, Kurzynski, D M, Boehm, J A, Rott-Petri, R F, Schell, P E, Allison   +4 more
openaire   +2 more sources

Leveraging large language models on free-text symptoms from participatory surveillance enhances pertussis forecasting in the United States

BMC Infectious Diseases
Background Declines in childhood vaccination in the U.S. have contributed to a resurgence of vaccine-preventable diseases, including a notable increase in pertussis cases. Traditional pertussis surveillance is limited by underdiagnosis and underreporting.
Luigi De Angelis, Samuele Tarallo, Caterina Rizzo, Autumn Gertz, Francesco Baglivo, John S. Brownstein, Benjamin Rader   +6 more
doaj   +1 more source

A National Study of Tetanus Vaccine Knowledge, Receipt and Acceptance Among Emergency Department Patients

Academic Emergency Medicine, Volume 33, Issue 9, September 2026.
ABSTRACT Objective The Tetanus, Diphtheria, Pertussis (Tdap, “tetanus”) vaccine is recommended for adults every 10 years. In a national sample of adult emergency department (ED) patients, we sought to determine (1) knowledge and up‐to‐date status of the tetanus vaccine; (2) reasons for nonreceipt of the vaccine; (3) vaccine acceptability if offered in ...
Francesco Sergi, Elisa Vaezazizi, Shaokui Ge, Christopher Alvarez, Jesus Torres, Brian Chinnock, Michael Gottlieb, Vijaya Arun Kumar, Kristin L. Rising, Efrat Rosenzweig Kean, Stephanie Eucker, Robert M. Rodriguez   +11 more
wiley   +1 more source

Bordetella pertussis surveillance in England and Wales: 1995–7

Epidemiology and Infection, 1999
Available data sources on disease due to Bordetella pertussis, including notifications, hospital admissions, deaths, and an enhanced laboratory-based surveillance system commenced in January 1994, were reviewed for the period 1995–7. Pertussis notifications continued their approximately 3-year cycle although at historically reduced levels.
P G, Van Buynder, D, Owen, J E, Vurdien, N J, Andrews, R C, Matthews, E, Miller   +5 more
openaire   +3 more sources

Pertussis surveillance in French hospitals: results from a 10 year period [PDF]

Eurosurveillance, 2007
We present 10 years of results from a paediatrician hospital network surveillance in France, set up in 1996 to monitor the trend of pertussis (whooping cough) in children and the impact of the vaccination strategies. Microbiologists from 43 hospitals that participate in the network on a voluntary basis notify pertussis diagnosis, and paediatricians ...
I Bonmarin, D Lévy-Bruhl, S Baron, N Guiso, E Njamkepo, V Caro, Collective Renacoq   +6 more
openaire   +2 more sources

Understanding the High Incidence of Pertussis in Norway: The Role of Test Activity

Acta Paediatrica, EarlyView.
Margrethe Greve‐Isdahl, Elina Seppälä   +1 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1673-1685, August 2026.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Pertussis Surveillance in Private Pediatric Practices, France, 2002–2006

Emerging Infectious Diseases, 2008
To the Editor: In France, pertussis epidemiology has been extensively studied since 1993. Immunization of children with a highly efficacious pertussis whole-cell (Pw) vaccine (Sanofi Pasteur MSD, Lyon, France) for 40 years (since 1966) has reduced the incidence of pertussis.
Nicole Guiso, France de La Rocque, Elisabeth Njamkepo, Aurelie Lécuyer, Corinne Levy, Olivier Romain, Franck Thollot, Véronique Abitbol, Benoit Soubeyrand, Robert Cohen, Thérapeutique Infantile du Val de Marne   +10 more
openaire   +3 more sources

Epidemiology of Pertussis After the COVID-19 Pandemic: Analysis of the Factors Involved in the Resurgence of the Disease in High-, Middle-, and Low-Income Countries

Vaccines
Pertussis is a highly contagious bacterial disease of the respiratory tract that can be prevented by vaccination. Before the COVID-19 pandemic, the vaccine coverage rate for the third dose of a DPT-containing vaccine was 86%, with large disparities among
Lucia F. Bricks, Juan C. Vargas-Zambrano, Denis Macina   +2 more
doaj   +1 more source

The cGAS–STING Pathway Drives Astrocyte‐Mediated Demyelination in Multiple Sclerosis Through Clusterin Secretion

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
In multiple sclerosis, astrocytes detect extracellular DNA via the cGAS–STING pathway, triggering Clusterin secretion that induces oligodendrocyte apoptosis and demyelination. Pharmacological STING inhibition with H‐151 suppresses this neurotoxic cascade, preserves myelin integrity, and ameliorates clinical disability in experimental autoimmune ...
Shengfei Hu, Xia Xiao, Xi Cheng, Yiying Huang, Tingting Cui, Shishi Shen, Chunping Cui, Li Xiao, Hanzhang Tan, Wei Qiu, Yipeng Zhao, Rui Li   +11 more
wiley   +1 more source