Results 51 to 60 of about 600,713 (168)

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Pertussis Surveillance—United States, 1989-1991

JAMA: The Journal of the American Medical Association, 1993
The licensure of whole-cell pertussis vaccine combined with diphtheria and tetanus toxoids as DTP in the 1940s--and its widespread use in infants and children--led to a dramatic decline in the incidence of reported pertussis. In the prevaccine era, the average annual incidence and mortality for reported pertussis were 150 cases and six deaths per 100 ...
S F, Davis, P M, Strebel, S L, Cochi, E R, Zell, S C, Hadler   +4 more
openaire   +3 more sources

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

MedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

Targeting the GPR183/EBI2‒oxysterol axis in tuberculosis: Immunometabolic regulation and prospects for host‐directed therapy

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
GPR183/EBI2 links oxysterol metabolism with immune‐cell positioning and macrophage function in tuberculosis. The 7α,25‐OHC‐GPR183 axis regulates macrophage trafficking, autophagy and type I interferon responses. GPR183 represents a potential immunometabolic target for host‐directed therapy against tuberculosis..
Junfei Wang, Yingnan Zhou, Xunming Ji, Haiping Zhao, Lingjun Zhan   +4 more
wiley   +1 more source

Safety Surveillance of Diphtheria and Tetanus Toxoids and Acellular Pertussis (DTaP) Vaccines [PDF]

Pediatrics, 2018
OBJECTIVE:To assess the safety of currently licensed diphtheria-tetanus-acellular pertussis (DTaP) vaccines in the United States by using data from the Vaccine Adverse Event Reporting System (VAERS), a spontaneous reporting surveillance system.METHODS:We searched VAERS for US reports of DTaP vaccinations occurring from January 1, 1991, through December
Pedro L, Moro, Silvia, Perez-Vilar, Paige, Lewis, Marthe, Bryant-Genevier, Hajime, Kamiya, Maria, Cano   +5 more
openaire   +2 more sources

RSV Monoclonal Antibody Implementation for At‐Risk Infants: Victoria, Australia's 2024 Experience

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background New respiratory syncytial virus (RSV) preventative programs are launching globally. Our Australian jurisdiction implemented RSV monoclonal antibody provision via pediatric and perinatal hospitals for highest risk neonates and infants.
Jane Tuckerman, Daryl R. Cheng, Guillian Hunter, Sonja Elia, Tara Hearn, Deepali Verma, Susan Jacobs, Jeremy Carr, Nigel W. Crawford   +8 more
wiley   +1 more source

Emergence of Bordetella holmesii–Associated Pertussis-Like Illness, Northern India, 2019–2023

Emerging Infectious Diseases
We investigated Bordetella holmesii and Bordetella pertussis in 935 suspected pertussis cases in northern India (2019–2023) using PCR and serology. B. holmesii showed increased prevalence in pertussis cases, particularly in older children, highlighting ...
Nishant Shekhar, Deepa Sharma, Surajit Chakraborty, Rajesh Kumar, Rajneesh Singh Rawat, Nirmal Kaundal, Pawan Kumar, Tigran Avagyan, Deeksha Chauhan, Neha Jain, Megha Sharma, Arun Kumar, Vikas Gautam   +12 more
doaj   +1 more source

An epidemiological investigation of the 2019 suspected pertussis outbreak in northwestern Nigeria

SAGE Open Medicine, 2021
Introduction: In 2019, we investigated the profile of the cases and controls and the determinants of pertussis transmission in Kebbi State, Northwestern Nigeria, to inform better immunization and surveillance strategies.
Omoleke Semeeh, Biniam Getachew, Yusuf Taofik, Lukman Surajudeen, Assad Hassan, Bello Nagudale   +5 more
doaj   +1 more source

Understanding the Epidemiology of Pertussis in Denmark

Acta Paediatrica, EarlyView.
Tine Dalby, Aoife Ronayne, Peter Henrik Andersen   +2 more
wiley   +1 more source

Microbiological, Molecular Diagnosis and Antimicrobial Resistance of Bordetella bronchiseptica in the Equine Reproductive Tract in Brazil

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
First report of Bordetella bronchiseptica in the reproductive tract of Brazilian mares. Uterine lavage samples from mares with endometritis and infertility were positive by culture, PCR (237 bp flaA), sequencing and phylogenetic analysis. Isolates showed multidrug resistance, emphasizing the relevance of this pathogen in equine reproductive disorders ...
Samira Salim Mello Gallo, Maria de Lourdes Amaral Bernardino, Luiz Antonio Silveira da Motta Júnior, Francisco Carlos Rodrigues de Oliveira, Marcos Antonio Pessanha Barreto, Marcio Manhães Folly   +5 more
wiley   +1 more source