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Safety and immunogenicity of an acellular pertussis vaccine containing genetically detoxified pertussis toxin administered to pregnant women living with and without HIV and their newborns (WoMANPOWER): a randomised controlled trial in Uganda.

open access: yesLancet Glob Health
Nakabembe E   +22 more
europepmc   +1 more source

Safety and Immunogenicity of an Acellular Pertussis Vaccine Containing Genetically-Detoxified Pertussis Toxin Administered to Pregnant Women Living with and Without HIV and Their New-Borns: A Randomised Controlled Trial in Uganda

open access: green
Eve Nakabembe   +21 more
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Pertussis vaccines

Current Opinion in Pediatrics, 2022
Purpose of review Pertussis is a vaccine preventable cough illness. It can be controlled by universal pertussis vaccination. Recent findings Pertussis cases and deaths in children are at a record low number.
James D, Cherry, Saba, Doustmohammadi
openaire   +2 more sources

Pertussis Vaccines

Pediatric Clinics of North America, 1990
Concern over adverse reactions temporally associated with whole cell pertussis vaccine and advances in the understanding of the Bordetella pertussis organism have led to a new generation of more purified acellular vaccines. The biology of the pertussis organism, epidemiology of disease, vaccine development over the decades, and vaccine efficacy and ...
K M, Edwards, D T, Karzon
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Acellular pertussis vaccines

Current Problems in Pediatrics, 2000
Although whole-cell pertussis vaccines have been highly effective in preventing whooping cough, their common and burdensome adverse reactions have spurred the development of safer alternatives. Seven acellular vaccines are licensed in one or more countries; four have been licensed thus far in the United States, and more may follow.
M R, Schleiss, K, Dahl
openaire   +4 more sources

Pertussis vaccine controversies and acellular pertussis vaccine

The Indian Journal of Pediatrics, 2003
Pertussis still continues to cause significant morbidity and mortality worldwide. Because of the high reactogenicity of whole cell pertussis vaccine, it had evoked public controversy in several countries. In 1970 Japan abandoned use of whole cell pertussis vaccine and mounted efforts to develop better vaccine.
Raju C, Shah, Anuj R, Shah
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Improving pertussis vaccination

Human Vaccines, 2009
Despite a high vaccine coverage, pertussis has re-emerged and has become the most prevalent vaccine preventable disease in developed countries. The re-emergence of pertussis has been attributed to various factors, including increased awareness, improved diagnostics, suboptimal vaccines, waning vaccine-induced immunity and pathogen adaptation.
Guy A M, Berbers   +2 more
openaire   +2 more sources

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