Results 81 to 90 of about 636,928 (222)

Adenoviral-vectored vaccine against Bordetella pertussis fimbrial antigen induces partial protection in a mouse model

Vaccine: X
Pertussis has been resurgent in many countries worldwide despite good vaccine coverage. One hypothesis for this resurgence is that the current acellular pertussis (aP) vaccines, used in most developed countries, induce short-term protection, and do not ...
Alexa Dierig, Martina Kristof, Christina Dold, Elodie Lesne, Catpagavalli Asokanathan, Luke Blackwell, Barbara Bolgiano, Andrew R. Gorringe, Andrew J. Pollard, Kevin Markey, Christine S. Rollier   +10 more
doaj   +1 more source

Immunological and Clinical Benefits of Maternal Immunization Against Pertussis: A Systematic Review

Infectious Diseases and Therapy, 2019
Infants are vulnerable to pertussis infection particularly before initiation of pertussis vaccination. Maternal pertussis vaccination during pregnancy has been introduced in a number of countries in order to confer on young infants indirect protection ...
Charlotte Switzer, Caroline D’Heilly, Denis Macina   +2 more
doaj   +1 more source

Immunologic profiling of the infant immune response to whole-cell and acellular pertussis vaccines

npj Vaccines
Despite robust antibody responses, immunity induced by acellular pertussis vaccine (DTaP) wanes over time and risk of pertussis seems to be lower in children who receive whole-cell vaccine (DTP) as their first dose.
C. Buddy Creech, Mariana Leguia, Johannes B. Goll, Leigh M. Howard, Antón Vila-Sanjurjo, Sandra Yoder, Diana Juarez, Alejandra Garcia-Glaessner, Casey E. Gelber, Natalia Jimenez-Truque, Sami Cherikh, Ana I. Gil, James E. Crowe, Rubelio Cornejo Cotos, Kathryn M. Edwards, Claudio F. Lanata   +15 more
doaj   +1 more source

Do previously held vaccine attitudes dictate the extent and influence of vaccine information-seeking behavior during pregnancy?

Human Vaccines & Immunotherapeutics, 2019
Pregnancy represents a high information need state, where uncertainty around medical intervention is common. As such, the pertussis vaccination given during pregnancy presents a unique opportunity to study the interaction between vaccine attitudes and ...
Richard M. Clarke, Miroslav Sirota, Pauline Paterson   +2 more
doaj   +1 more source

Accelerating Control of Pertussis in England and Wales

Emerging Infectious Diseases, 2012
Results of an accelerated pertussis vaccination schedule for infants introduced in 1990 in England and Wales were examined. Earlier scheduling and sustained high vaccine coverage resulted in fewer reported cases of pertussis among infants, reinforcing ...
Helen Campbell, Gayatri Amirthalingam, Nick Andrews, Norman K. Fry, Robert C. George, Timothy Harrison, Elizabeth Miller   +6 more
doaj   +1 more source

Innovative adjuvant strategies for next-generation pertussis vaccines

Human Vaccines & Immunotherapeutics
The acellular pertussis (aP) vaccine has increasingly replaced the whole-cell pertussis (wP) vaccine due to its superior safety profile. However, the aP vaccine is less effective at preventing infection and transmission of Bordetella pertussis ...
Ge Yu, Wenqi Yang, Yubin Ma, Ning Zhang, Di Tang, Ye Jin, Liang Shi, Mengshu Wang, Dawei Liu, Changying Xue, Bingbing Sun   +10 more
doaj   +1 more source

Adaptive immune response to bordetella pertussis during vaccination and infection: emerging perspectives and unanswered questions

Expert Review of Vaccines
Introduction Whooping cough, also known as pertussis, remains a significant challenge as a vaccine-preventable disease worldwide. Since the switch from the whole-cell Pertussis (wP) vaccine to the acellular Pertussis vaccine (aP), cases of whooping cough
A-Reum Kim, Alessandro Sette, Ricardo da Silva Antunes   +2 more
doaj   +1 more source

Epidemiology of Pertussis After the COVID-19 Pandemic: Analysis of the Factors Involved in the Resurgence of the Disease in High-, Middle-, and Low-Income Countries

Vaccines
Pertussis is a highly contagious bacterial disease of the respiratory tract that can be prevented by vaccination. Before the COVID-19 pandemic, the vaccine coverage rate for the third dose of a DPT-containing vaccine was 86%, with large disparities among
Lucia F. Bricks, Juan C. Vargas-Zambrano, Denis Macina   +2 more
doaj   +1 more source

Immune response to pertussis vaccine in COPD patients. [PDF]

Sci Rep, 2023
Feredj E, Wiedemann A, Krief C, Maitre B, Derumeaux G, Chouaid C, Le Corvoisier P, Lacabaratz C, Gallien S, Lelièvre JD, Boyer L.   +10 more
europepmc   +1 more source

Evaluation of acellular pertussis vaccine: comparisons among different strains of mice. [PDF]

Emerg Microbes Infect, 2023
Wei J, Guang J, Wei C, Wang H, Zhou J, Li H, Wang L, Ma X, Yue B.   +8 more
europepmc   +1 more source