Results 71 to 80 of about 28,317 (188)

Immunological and Clinical Benefits of Maternal Immunization Against Pertussis: A Systematic Review

Infectious Diseases and Therapy, 2019
Infants are vulnerable to pertussis infection particularly before initiation of pertussis vaccination. Maternal pertussis vaccination during pregnancy has been introduced in a number of countries in order to confer on young infants indirect protection ...
Charlotte Switzer, Caroline D’Heilly, Denis Macina   +2 more
doaj   +1 more source

Adenoviral-vectored vaccine against Bordetella pertussis fimbrial antigen induces partial protection in a mouse model

Vaccine: X
Pertussis has been resurgent in many countries worldwide despite good vaccine coverage. One hypothesis for this resurgence is that the current acellular pertussis (aP) vaccines, used in most developed countries, induce short-term protection, and do not ...
Alexa Dierig, Martina Kristof, Christina Dold, Elodie Lesne, Catpagavalli Asokanathan, Luke Blackwell, Barbara Bolgiano, Andrew R. Gorringe, Andrew J. Pollard, Kevin Markey, Christine S. Rollier   +10 more
doaj   +1 more source

Adaptive immune response to bordetella pertussis during vaccination and infection: emerging perspectives and unanswered questions

Expert Review of Vaccines
Introduction Whooping cough, also known as pertussis, remains a significant challenge as a vaccine-preventable disease worldwide. Since the switch from the whole-cell Pertussis (wP) vaccine to the acellular Pertussis vaccine (aP), cases of whooping cough
A-Reum Kim, Alessandro Sette, Ricardo da Silva Antunes   +2 more
doaj   +1 more source

Pertussis Vaccination and Pregnancy [PDF]

Clinical Infectious Diseases, 2013
Leuridan, E., Hoang, T.T.H., Dang, D.A., van Damme, P.   +3 more
openaire   +3 more sources

Epidemiology of Pertussis After the COVID-19 Pandemic: Analysis of the Factors Involved in the Resurgence of the Disease in High-, Middle-, and Low-Income Countries

Vaccines
Pertussis is a highly contagious bacterial disease of the respiratory tract that can be prevented by vaccination. Before the COVID-19 pandemic, the vaccine coverage rate for the third dose of a DPT-containing vaccine was 86%, with large disparities among
Lucia F. Bricks, Juan C. Vargas-Zambrano, Denis Macina   +2 more
doaj   +1 more source

Pertussis vaccination in newborns

Expert Review of Vaccines, 2009
Bordetella pertussis remains in fifth place among the leading etiologies of vaccine-preventable deaths in children around the world. The impact of this disease is considerable in North America, Latin America, Europe and other parts of the world. Therefore, new vaccination strategies have been recommended in the last decade, predominantly to protect ...
openaire   +2 more sources

Pertussis vaccine. [PDF]

BMJ, 1981
openaire   +2 more sources

Innovative adjuvant strategies for next-generation pertussis vaccines

Human Vaccines & Immunotherapeutics
The acellular pertussis (aP) vaccine has increasingly replaced the whole-cell pertussis (wP) vaccine due to its superior safety profile. However, the aP vaccine is less effective at preventing infection and transmission of Bordetella pertussis ...
Ge Yu, Wenqi Yang, Yubin Ma, Ning Zhang, Di Tang, Ye Jin, Liang Shi, Mengshu Wang, Dawei Liu, Changying Xue, Bingbing Sun   +10 more
doaj   +1 more source

Protective effectiveness of acellular diphtheria-tetanus-pertussis vaccine against pertussis in infants and young children aged 2 years and under in Gansu province: a retrospective cohort study based on population-based surveillance data

Zhongguo gonggong weisheng
ObjectiveTo evaluate the vaccine effectiveness (VE) of the adsorbed acellular diphtheria-tetanus-pertussis (DTaP) vaccine in infants and young children aged 2 years and under in Gansu province, thereby providing evidence for optimizing the immunization ...
Yongzhuo JIAO, Jing AN, Shuyu LIU, Xuefeng LIANG, Xiaoshu ZHANG   +4 more
doaj   +1 more source

Development of High-Throughput Serum Bactericidal Assays for Bordetella pertussis to Evaluate BPZE1

Vaccines
Background/Objectives: Pertussis, caused by Bordetella pertussis, remains a global health problem, despite high vaccine coverage. In countries with high acellular pertussis vaccine (aPV) coverage, pertactin-negative B.
Peter Goldstein, Tania Gensale, Shannon Harris, Tina M. Green, Stephanie Noviello, Keith Rubin, Camille Locht, Breeze Cavell, Andrew Gorringe, Luc Gagnon   +9 more
doaj   +1 more source