Results 51 to 60 of about 26,947 (190)

Long‐acting monoclonal antibodies and the evolving landscape of infant respiratory syncytial virus prevention

Pediatric Investigation, EarlyView.
Ran Wang, Bahaa Abu‐Raya, Hala Obeid, Zhengde Xie   +3 more
wiley   +1 more source

Structured Antenatal Counselling Improves Maternal Influenza and Pertussis Uptake: A Prospective Comparative Study in Greece

Acta Paediatrica, EarlyView.
ABSTRACT Aim Maternal immunization is essential for preventing severe influenza and pertussis in pregnant women and young infants. Despite clear recommendations, uptake in Greece remains suboptimal, and evidence on effective antenatal interventions is limited.
A. Drougia, F. Ladomenou, E. Sourla, A. Klapas, P. Pappa, C. Skendou, M. Paschopoulos, V. Giapros   +7 more
wiley   +1 more source

Update on Selected Adverse Events of Concern Following Immunization With Acellular Pertussis Vaccines, a Narrative Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim To provide an update paper on evidence of adverse events of concern following immunization (AEFI) with pertussis vaccines, focusing primarily on acellular (aP) vaccines. Methods Evidence was synthesised from epidemiological studies, systematic reviews over recent decades, expert interpretations in reviews from relevant research teams and ...
Lennart Nilsson, Jann Storsaeter
wiley   +1 more source

Pertactin deficiency of Bordetella pertussis: Insights into epidemiology, and perspectives on surveillance and public health impact

Human Vaccines & Immunotherapeutics
Pertussis resurgence has been documented even in countries with high pediatric vaccine coverage. The proportion of Bordetella pertussis isolates not expressing pertactin (PRN) has increased in several countries where acellular pertussis (aP) vaccines are
Ulrich Heininger, Helena Martini, Jennifer Eeuwijk, Ivana Prokić, Adrienne P. Guignard, Elisa Turriani, Maurine Duchenne, Valérie Berlaimont   +7 more
doaj   +1 more source

Understanding the Epidemiology of Pertussis in Denmark

Acta Paediatrica, EarlyView.
Tine Dalby, Aoife Ronayne, Peter Henrik Andersen   +2 more
wiley   +1 more source

A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA

Acta Paediatrica, EarlyView.
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley   +1 more source

Acellular pertussis vaccines effectiveness over time: A systematic review, meta-analysis and modeling study.

PLoS ONE, 2018
BackgroundAcellular pertussis vaccine studies postulate that waning protection, particularly after the adolescent booster, is a major contributor to the increasing US pertussis incidence.
Ayman Chit, Hossein Zivaripiran, Thomas Shin, Jason K H Lee, Antigona Tomovici, Denis Macina, David R Johnson, Michael D Decker, Jianhong Wu   +8 more
doaj   +1 more source

Acellular Pertussis Vaccine Inhibits Bordetella pertussis Clearance from the Nasal Mucosa of Mice

Vaccines, 2020
Bordetella pertussis whole-cell vaccines (wP) caused a spectacular drop of global pertussis incidence, but since the replacement of wP with acellular pertussis vaccines (aP), pertussis has resurged in developed countries within 7 to 12 years of the ...
Jana Holubová, Ondřej Staněk, Ludmila Brázdilová, Jiří Mašín, Ladislav Bumba, Andrew R. Gorringe, Frances Alexander, Peter Šebo   +7 more
doaj   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Pertussis vaccination in pregnancy [PDF]

Human Vaccines & Immunotherapeutics, 2016
Pertussis has had a resurgence with the highest incidence and complication rates in young infants, and deaths occurring mainly at < age 3 months. Infants are infected by older individuals whose immunity has waned. Strategies such as targeted immunization of infant caregivers have had limited success.
openaire   +2 more sources