Results 51 to 60 of about 32,413 (228)

Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model

Frontiers in Immunology, 2022
Pertussis, caused by the gram-negative bacterium Bordetella pertussis, is a highly contagious respiratory disease. Intranasal vaccination is an ideal strategy to prevent pertussis, as the nasal mucosa represents the first-line barrier to B.
Wenwen Jiang, Xiaoyu Wang, Yuhao Su, Lukui Cai, Jingyan Li, Jiangli Liang, Qin Gu, Mingbo Sun, Mingbo Sun, Li Shi   +9 more
doaj   +1 more source

Swedish Infants Developed Pertussis at a Younger Age if Their Mother Was the Possible Source of Infection in 2009–2015

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to investigate the possible source of laboratory‐confirmed pertussis in infants under 6 months of age. Methods This nationwide prospective study was based on laboratory‐confirmed cases reported in the enhanced pertussis surveillance in Sweden from 2009 to 2015. The parents or carers of 345 infants were interviewed
Bernice Aronsson, Lennart Nilsson, Jann Storsaeter, Henrik Källberg, Emma Appelqvist   +4 more
wiley   +1 more source

Advance system testing: Vaccine benefit studies using multi-country electronic health data - The example of pertussis vaccination

, 2020
The Accelerated Development of VAccine benefit-risk Collaboration in Europe (ADVANCE), a public-private consortium, implemented and tested a distributed network system for the generation of evidence on the benefits-risks of marketed vaccines in Europe ...
de, Lusignan S, Martín-Merino, E, Correa, A, Tramontan, L, de, Ridder M, McGee, C, Duarte-Salles, T, Huerta-Alvarez, C, Braeye, T, Tin, Tin Htar M   +9 more
core   +1 more source

What do Parents Learn by Reading a DPT Vaccine Information Form?

Canadian Journal of Infectious Diseases, 1994
Objective: Information forms are commonly used to inform parents about childhood vaccination. This study assessed the knowledge of mothers about pertussis and pertussis vaccine before and after reading a form about diphtheria-pertussis-tetanus (dpt ...
Ronald Gold, Gordean L Bjornson
doaj   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Purification design and practice for pertactin, the third component of acellular pertussis vaccine, from Bordetella pertussis

, 2016
Development of acellular pertussis vaccine (aPV) requires purification of several components from Bordetella pertussis. While the components pertussis toxin (PT) and filamentous hemagglutinin (FHA) have been successfully purified, the third component ...
Li, Zenglan, Zhang, Songping, Li, Zhengjun, Zhang, Guifeng, Wang, Qi, Zhang, Yan, Ma, Guanghui, Su, Zhiguo, Liu, Yongdong, Luo, Jian   +9 more
core   +1 more source

Factors affecting antibody responses to immunizations in infants born to women immunized against pertussis in pregnancy and unimmunized women: Individual-Participant Data Meta-analysis

, 2021
BACKGROUND: Exploring factors that affect immune responses to immunizations in infants born to women immunized with tetanus-diphtheria-acellular-pertussis (Tdap) in pregnancy compared with unimmunized women is important in designing immunization programs.
Halperin, Scott A, Kampmann, Beate, Barug, Daan, Abu-Raya, Bahaa, Halperin, Scott A., Rice, Thomas F, Leuridan, Elle, Leuridan, Elke, Sadarangani, Manish, Rice, Thomas F., Munoz, Flor M, Holder, Beth, Maertens, Kirsten, Curtis, Nigel, Munoz, Flor M., Rots, Nynke, Zimmermann, Petra   +16 more
core   +1 more source

Acellular and "low" pertussis vaccines: adverse events and the role of mutations Vacinas pertussis acelular e pertussis "low": eventos adversos e o papel das mutações

Revista do Instituto de Medicina Tropical de São Paulo, 2009
Objective: to discuss the current PAHO recommendation that does not support the substitution of traditional cellular DTP vaccine by acellular DTP, and the role of mutations, in humans, as the main cause of rare adverse events, such as epileptic-like ...
Hisako G. Higashi, Expedito Luna, Alexander R. Precioso, Marluce Vilela, Flávia S. Kubrusly, Waldely O. Dias, Isaias Raw   +6 more
doaj   +1 more source

Differential expression of type III effector BteA protein due to IS481 insertion in Bordetella pertussis. [PDF]

PLoS ONE, 2011
BACKGROUND: Bordetella pertussis is the primary etiologic agent of the disease pertussis. Universal immunization programs have contributed to a significant reduction in morbidity and mortality of pertussis; however, incidence of the disease, especially ...
Hyun-Ja Han, Asaomi Kuwae, Akio Abe, Yoshichika Arakawa, Kazunari Kamachi   +4 more
doaj   +1 more source

Rationale for Recommending Varicella Vaccination Into the Swedish National Immunisation Programme

Acta Paediatrica, EarlyView.
ABSTRACT Aim Under Swedish law, a vaccination may be included in the National Immunisation Programme (NIP) if it effectively prevents transmission in the population, is cost‐effective and aligns with ethical and humanitarian principles. The Public Health Agency of Sweden (PHAS) evaluated these criteria for introducing varicella vaccination. Methods The
Annika Ersson, Kari Johansen, Sören Andersson   +2 more
wiley   +1 more source