Results 31 to 40 of about 32,413 (228)

Pertussis post-exposure prophylaxis among household contacts: a cost-utility analysis. [PDF]

, 2015
BACKGROUND: Recent pertussis outbreaks have prompted re-examination of post-exposure prophylaxis (PEP) strategies, when immunization is not immediately protective.
Crowcroft, Natasha S, Crowcroft Natasha S., Sander Beate, Natasha S Crowcroft, Thampi, Nisha, Nisha Thampi, Gurol-Urganci Ipek, Thampi Nisha, Gurol-Urganci, Ipek, Beate Sander, Ipek Gurol-Urganci, Sander, Beate   +11 more
core   +1 more source

Assessment of Pertussis Vaccine Protective Effectiveness in Children in the Amhara Regional State, Ethiopia

International Journal of Microbiology, 2020
Background. Bordetella pertussis is a human pathogen which causes pertussis, or whooping cough. The diphtheria-tetanus-pertussis immunization has significantly reduced the morbidity and mortality of pertussis globally.
Solomon Taye, Belay Tessema, Baye Gelaw, Feleke Moges   +3 more
doaj   +1 more source

A Pertussis Outer Membrane Vesicle-Based Vaccine Induces Lung-Resident Memory CD4 T Cells and Protection Against Bordetella pertussis, Including Pertactin Deficient Strains

Frontiers in Cellular and Infection Microbiology, 2019
Pertussis is a respiratory infectious disease that has been resurged during the last decades. The change from the traditional multi-antigen whole-cell pertussis (wP) vaccines to acellular pertussis (aP) vaccines that consist of a few antigens formulated ...
María Eugenia Zurita, Mieszko M. Wilk, Francisco Carriquiriborde, Erika Bartel, Griselda Moreno, Alicja Misiak, Kingston H. G. Mills, Daniela Hozbor   +7 more
doaj   +1 more source

Pertussis Toxin: A Key Component in Pertussis Vaccines?

Toxins, 2019
B. pertussis is a human-specific pathogen and the causative agent of whooping cough. The ongoing resurgence in pertussis incidence in high income countries is likely due to faster waning of immunity and increased asymptomatic colonization in individuals ...
Kelsey A. Gregg, Tod J. Merkel
doaj   +1 more source

Pertussis Vaccines Working Group update [PDF]

01-Pertussis-Sawyer ...

core   +6 more sources

A novel method for the extraction of outer membrane vesicles (OMVs) from Bordetella pertussis Tohama strain

Iranian Journal of Microbiology, 2020
Background and Objectives: There are many pertussis outbreaks which is mainly due to the reduction in the immunity of acellular pertussis (aP) vaccines. Therefore, there is a crucial necessity to develop a new generation of pertussis vaccine.
Mohammad Sekhavati, Ashraf Mohabati Mobarez, Seyed Davar Siadat, Mojtaba Noofeli   +3 more
doaj   +1 more source

Evaluation of Whole-Cell and Acellular Pertussis Vaccines in the Context of Long-Term Herd Immunity

Vaccines, 2022
After the pertussis vaccine had been introduced in the 1940s and was shown to be very successful in reducing the morbidity and mortality associated with the disease, the possibility of improving both vaccine composition and vaccination schedules has ...
Ewa Szwejser-Zawislak, Mieszko M. Wilk, Piotr Piszczek, Justyna Krawczyk, Daria Wilczyńska, Daniela Hozbor   +5 more
doaj   +1 more source

An open-label randomized clinical trial of prophylactic paracetamol coadministered with 7-valent pneumococcal conjugate vaccine and hexavalent diphtheria toxoid, tetanus toxoid, 3-component acellular pertussis, hepatitis B, inactivated poliovirus, and Haemophilus influenzae type b vaccine

, 2013
BACKGROUND: In two clinical trials, low-grade fever was observed more frequently after coadministration than after separate administration of two recommended routine pediatric vaccines.
Rose, Markus A., William C Gruber, Sherryl Baker, Christine Juergens, Beate Schmoele-Thoma, Gruber, William C., Stefan Zielen, Zielen, Stefan, Jürgens, Christine, Schmoele-Thoma, Beate, Baker, Sherryl, Markus A Rose   +11 more
core   +1 more source

Incidence and mortality of pertussis disease in infants <12 months of age following introduction of pertussis maternal universal mass vaccination in Bogotá, Colombia

, 2020
Background Maternal immunization with tetanus, diphtheria, and acellular pertussis (Tdap) vaccine confers protection to young infants. We aimed to describe trends in pertussis incidence and associated mortality in children aged
DeAntonio, Rodrigo, Cáceres, Diana Carolina, Devadiga, Raghavendra, Martínez, Sandra P., Carrasquilla, Gabriel, Porras-Ramírez, Alexandra   +5 more
core   +1 more source

Comparative study of a whole-cell pertussis vaccine and a recombinant acellular pertussis vaccine.

, 1994
The safety and immunogenicity of an acellular pertussis vaccine containing the genetically detoxified pertussis toxin PT-9K/129G, filamentous hemagglutinin, and pertactin, together with diphtheria and tetanus toxoids, were compared with those of a whole ...
RAPPUOLI R. AND THE ITALIAN MULTICENTER GROUP FOR THE STUDY OF RECOMBINANT ACELLULAR PERTUSSIS VACCINE, PEPPOLONI, Samuele, MAIDA A., FURLAN R., UXA F., CARAPELLA DE LUCA E., NENCIONI L., CONTU B., TITONE L., MOIRAGHI A., STRAMARE D., DI PISA F., PODDA A.   +12 more
core   +2 more sources