Results 11 to 20 of about 26,947 (190)

Less reactogenic whole-cell pertussis vaccine confers protection from Bordetella pertussis infection [PDF]

open access: yesmSphere
Pertussis resurged over the last decade in most countries that replaced the traditional whole-cell pertussis vaccines (wP) by the less reactogenic acellular pertussis vaccines (aP).
Karolína Škopová   +6 more
doaj   +2 more sources

Pertussis Vaccine Candidate Based on Outer Membrane Vesicles Derived From Biofilm Culture [PDF]

open access: yesFrontiers in Immunology, 2021
Outer membrane vesicles (OMV) derived from Bordetella pertussis—the etiologic agent of the resurgent disease called pertussis—are safe and effective in preventing bacterial colonization in the lungs of immunized mice.
Francisco Carriquiriborde   +9 more
doaj   +2 more sources

Pertussis Vaccine [PDF]

open access: yesPediatric Infectious Disease Journal, 2009
A critical level of serum IgG pertussis toxin antibody is both essential and sufficient to confer individual and herd immunity to pertussis. Monocomponent pertussis toxoid conferred such immunity in Sweden and in Denmark. We refute the notion that filamentous hemagglutinin, pertactin, and fimbriae add to the immunity conferred by pertussis toxoid and ...
John B, Robbins   +5 more
openaire   +2 more sources

Evaluation of Immunobiological Properties of Bordetella pertussis Vaccine Strains

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
The study performed as part of evaluation of immunobiological properties of Bordetella pertussis vaccine strains offered an opportunity to standardize pertussis bacterial mass based on the content of surface antigens — agglutinogens 1, 2 and 3.
I. A. Alekseeva, O. V. Perelygina
doaj   +1 more source

The association between vaccine hesitancy and pertussis: a systematic review and meta-analysis

open access: yesItalian Journal of Pediatrics, 2023
Background Robust routine immunization schedules for pertussis-containing vaccines have been applied for years, but pertussis outbreaks remain a worldwide problem. This study aimed to investigate the association between vaccine hesitancy and pertussis in
Yuning Wang   +5 more
doaj   +1 more source

Expression of Bordetella pertussis Antigens Fused to Different Vectors and Their Effectiveness as Vaccines

open access: yesVaccines, 2021
Pertussis is an acute respiratory tract infection caused by Bordetella pertussis. Even though its current vaccine coverage is relatively broad, they still have some shortcomings such as short protection time and might be incapable of blocking the spread ...
Han Xu   +10 more
doaj   +1 more source

Rare Detection of Bordetella pertussis Pertactin-Deficient Strains in Argentina

open access: yesEmerging Infectious Diseases, 2019
Pertussis resurgence had been attributed to waning vaccine immunity and Bordetella pertussis adaptation to escape vaccine-induced immunity. Circulating bacteria differ genotypically from strains used in production of pertussis vaccine.
Francisco Carriquiriborde   +6 more
doaj   +1 more source

Immunogenicity of a Candidate DTacP-sIPV Combined Vaccine and Its Protection Efficacy against Pertussis in a Rhesus Macaque Model

open access: yesVaccines, 2021
The research and development of a pertussis-combined vaccine using a novel inactivated poliovirus vaccine made from the Sabin strain (sIPV) is of great significance in the polio eradication project and to address the recent resurge in pertussis.
Xiaoyu Wang   +7 more
doaj   +1 more source

Assessment of Pertussis Vaccine Protective Effectiveness in Children in the Amhara Regional State, Ethiopia

open access: yesInternational Journal of Microbiology, 2020
Background. Bordetella pertussis is a human pathogen which causes pertussis, or whooping cough. The diphtheria-tetanus-pertussis immunization has significantly reduced the morbidity and mortality of pertussis globally.
Solomon Taye   +3 more
doaj   +1 more source

A Pertussis Outer Membrane Vesicle-Based Vaccine Induces Lung-Resident Memory CD4 T Cells and Protection Against Bordetella pertussis, Including Pertactin Deficient Strains

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Pertussis is a respiratory infectious disease that has been resurged during the last decades. The change from the traditional multi-antigen whole-cell pertussis (wP) vaccines to acellular pertussis (aP) vaccines that consist of a few antigens formulated ...
María Eugenia Zurita   +7 more
doaj   +1 more source

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