Results 1 to 10 of about 6,623 (181)

Liposome and QS-21 Combined Adjuvant Induces theHumoral and Cellular Responses of Acellular Pertussis Vaccine in a Mice Model [PDF]

Vaccines, 2023
The resurgence of pertussis in vaccinated communities may be related to the reduced long-term immunity induced by acellular pertussis vaccines. Therefore, developing improved pertussis vaccine candidates that could induce strong Th1 or Th17 cellular ...
Baifeng Yang, Dewu Zhu, Yisi Zhou, Beizhe Gong, Yuan Hu, Jiayou Zhang, Shihe Huang, Xuanxuan Nian, Xinghang Li, Xinguo Li, Kai Duan, Xiaoming Yang   +11 more
doaj   +2 more sources

An Expert Perspective on a New Recombinant Pertussis-Only Vaccine and Its Potential Clinical and Programmatic Advantages in Australia, New Zealand, and Beyond [PDF]

Vaccines
Despite high childhood coverage and booster doses of pertussis vaccination across the life course, pertussis (whooping cough) outbreaks continue to occur, including in Australia and New Zealand.
Peter McIntyre, Anita H. J. van den Biggelaar, Frank Beard, Mary Nowlan, Annette K. Regan, Rodney Pearce, Terry Nolan, Catherine Hughes, Peter Richmond   +8 more
doaj   +2 more sources

Bordetella pertussis Infection: From Immune Pathogenesis to Next-Generation Vaccines [PDF]

Vaccines
Pertussis is a highly contagious respiratory infection caused by Bordetella pertussis and remains a persistent global health challenge despite widespread vaccination. This review aims to analyze the immune pathogenesis of B.
Vasiliki E. Georgakopoulou, Vassiliki C. Pitiriga   +1 more
doaj   +2 more sources

Acellular Pertussis Vaccine Components: Today and Tomorrow [PDF]

Vaccines, 2020
Eric T Harvill, Kalyan K Dewan, Bodo Linz   +2 more
exaly   +2 more sources

Comparing the pertussis antibody levels of healthy children immunized with four doses of DTap-IPV/Hib (Pentaxim) combination vaccine and DTaP vaccine in Quzhou, China

Frontiers in Immunology, 2023
Despite the high coverage of pertussis vaccines in high-income countries, pertussis resurgence has been reported in recent years, and has stimulated interest in the effects of vaccines and vaccination strategies. Immunoglobulin G (IgG) antibodies against
Zhiying Yin, Zhiying Yin, Canjie Zheng, Quanjun Fang, Tingcui Wen, Shuangqing Wang, Junji Li, Xiaoying Gong, Ziling Xiang   +8 more
doaj   +1 more source

Pertussis vaccines and the role of Bordetella pertussis lipooligosaccharide in the immune response to pertussis infection and vaccination

Биопрепараты: Профилактика, диагностика, лечение, 2021
Some scientific publications contain data suggesting the “return” or “resurgence” of pertussis. Prevention and elimination of pertussis can only be achieved by extensive immunisation of susceptible populations with a highly effective vaccine.
I. A. Alekseeva, O. V. Perelygina, E. D. Kolyshkina   +2 more
doaj   +1 more source

Age and Primary Vaccination Background Influence the Plasma Cell Response to Pertussis Booster Vaccination

Vaccines, 2022
Pertussis is a vaccine-preventable disease caused by the bacterium Bordetella pertussis. Over the past years, the incidence and mortality of pertussis increased significantly. A possible cause is the switch from whole-cell to acellular pertussis vaccines,
Annieck M. Diks, Pauline Versteegen, Cristina Teodosio, Rick J. Groenland, Bas de Mooij, Anne-Marie Buisman, Alba Torres-Valle, Martín Pérez-Andrés, Alberto Orfao, Guy A. M. Berbers, Jacques J. M. van Dongen, Magdalena A. Berkowska, on behalf of the IMI-2 PERISCOPE Consortium   +12 more
doaj   +1 more source

Responses to an acellular pertussis booster vaccination in children, adolescents, and young and older adults: A collaborative study in Finland, the Netherlands, and the United Kingdom

EBioMedicine, 2021
Background: Pertussis can lead to serious disease and even death in infants. Older adults are more vulnerable to complications as well. In high-income countries, acellular pertussis vaccines are used for priming vaccination.
Pauline Versteegen, Marta Valente Pinto, Alex M. Barkoff, Pieter G.M. van Gageldonk, dr. Jan van de Kassteele, dr. Marlies A. van Houten, prof. Elisabeth A.M. Sanders, prof. Ronald de Groot, dr. Dimitri A. Diavatopoulos, dr. Sagida Bibi, dr. Raakel Luoto, prof. Qiushui He, dr. Anne-Marie Buisman, dr. Dominic F. Kelly, prof. Jussi Mertsola, dr. Guy A.M. Berbers   +15 more
doaj   +1 more source

An infant who suffered seizures many times after pentavalent vaccination: A case report

İstanbul Kuzey Klinikleri, 2020
Although rare, serious adverse effects may be seen after vaccination. Especially, the whole-cell pertussis vaccine has been held responsible for neurological side effects, as the most important problem in vaccination.
Meryem Erat Nergiz, Hande Yetişgin, Alperen Aydın, Gulsum Iclal Bayhan, Aysegul Nese Citak Kurt   +4 more
doaj   +1 more source

Evaluation of Whole-Cell and Acellular Pertussis Vaccines in the Context of Long-Term Herd Immunity

Vaccines, 2022
After the pertussis vaccine had been introduced in the 1940s and was shown to be very successful in reducing the morbidity and mortality associated with the disease, the possibility of improving both vaccine composition and vaccination schedules has ...
Ewa Szwejser-Zawislak, Mieszko M. Wilk, Piotr Piszczek, Justyna Krawczyk, Daria Wilczyńska, Daniela Hozbor   +5 more
doaj   +1 more source