Results 11 to 20 of about 6,623 (181)

Seroprevalence of antibodies against diphtheria, tetanus, and pertussis among healthy Thai adolescents

International Journal of Infectious Diseases, 2020
Objective: To determine the seroprevalence of antibodies against of diphtheria, tetanus, and pertussis among Thai adolescents. Methods: A cross-sectional study was conducted among Thai adolescents aged 11–20 years who had completed five doses of ...
Pimpika Hanvatananukul, Chanidapa Prasarakee, Saowalak Sarachai, Linda Aurpibul, Kamolrawee Sintupat, Ratchaneekorn Khampan, Jutamad Saheng, Tavitiya Sudjaritruk   +7 more
doaj   +1 more source

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination

Scientific Reports, 2022
Infection is the most common cause of mortality early in life, yet the broad potential of immunization is not fully realized in this vulnerable population. Most vaccines are administered during infancy and childhood, but in some cases the full benefit of
David J. Dowling, Soumik Barman, Alyson J. Smith, Francesco Borriello, Danielle Chaney, Spencer E. Brightman, Gandolina Melhem, Byron Brook, Manisha Menon, Dheeraj Soni, Simone Schüller, Karthik Siram, Etsuro Nanishi, Hélène G. Bazin, David J. Burkhart, Ofer Levy, Jay T. Evans   +16 more
doaj   +1 more source

A novel vaccine formulation candidate based on lipooligosaccharides and pertussis toxin against Bordetella pertussis

Frontiers in Immunology, 2023
Pertussis is a severe human respiratory tract infectious disease caused by Bordetella pertussis that primarily affects infants and young children.
Jingjing Gao, Linlin Huang, Shuquan Luo, Ruijie Qiao, Fanglei Liu, Xin Li, Xin Li   +6 more
doaj   +1 more source

Association between pertussis vaccination coverage and other sociodemographic factors and pertussis incidence using surveillance data

Epidemics, 2023
Routine vaccination with pertussis vaccines has been successful in driving down pertussis mortality and morbidity globally. Despite high vaccination coverage, countries such as Australia, USA, and UK have experienced increase in pertussis activity over ...
Madhura S. Rane, Jonathan Wakefield, Pejman Rohani, M. Elizabeth Halloran   +3 more
doaj   +1 more source

Pertactin-Deficient Bordetella pertussis, Vaccine-Driven Evolution, and Reemergence of Pertussis

Emerging Infectious Diseases, 2021
Recent reemergence of pertussis (whooping cough) in highly vaccinated populations and rapid expansion of Bordetella pertussis strains lacking pertactin (PRN), a common acellular vaccine antigen, have raised the specter of vaccine-driven evolution and ...
Longhuan Ma, Amanda Caulfield, Kalyan K. Dewan, Eric T. Harvill   +3 more
doaj   +1 more source

Safety and Immunogenicity of a Fully Liquid Vaccine Containing Five-Component Pertussis-Diphtheria-Tetanus-Inactivated Poliomyelitis-Haemophilus influenzae Type B Conjugate Vaccines Administered at Two, Four, Six and 18 Months of Age

Canadian Journal of Infectious Diseases and Medical Microbiology, 2007
OBJECTIVE: The safety, immunogenicity and lot consistency of a fully liquid, five-component acellular pertussis combination vaccine, comprised of diphteria, tetanus and acellular pertussis, inactivated polio vaccine, Haemophilus influenzae type b (DTaP ...
Ronald Gold, Luis Barreto, Santiago Ferro, John Thippawong, Roland Guasparini, William Meekison, Margaret Russell, Elaine Mills, Dana Harrison, Pierre Lavigne   +9 more
doaj   +1 more source

Acellular pertussis vaccines effectiveness over time: A systematic review, meta-analysis and modeling study.

PLoS ONE, 2018
BackgroundAcellular pertussis vaccine studies postulate that waning protection, particularly after the adolescent booster, is a major contributor to the increasing US pertussis incidence.
Ayman Chit, Hossein Zivaripiran, Thomas Shin, Jason K H Lee, Antigona Tomovici, Denis Macina, David R Johnson, Michael D Decker, Jianhong Wu   +8 more
doaj   +1 more source

Acellular Pertussis Vaccines Induce Anti-pertactin Bactericidal Antibodies Which Drives the Emergence of Pertactin-Negative Strains

Frontiers in Microbiology, 2020
Despite high vaccination coverage, Bordetella pertussis the causative agent of whooping cough is still a health concern worldwide. A resurgence of pertussis cases has been reported, particularly in countries using acellular vaccines with waning immunity ...
Elodie Lesne, Breeze E. Cavell, Irene Freire-Martin, Ruby Persaud, Frances Alexander, Stephen Taylor, Mary Matheson, Cécile A. C. M. van Els, Andrew Gorringe   +8 more
doaj   +1 more source

Acellular pertussis vaccine for adolescents [PDF]

Jornal de Pediatria, 2006
The use of whole-cell pertussis vaccine has led to a significant decline in incidence of the disease among children. This change in the epidemiological profile led to an increased number of cases among teenagers and adults, as a result of loss of immunity to the disease or vaccine after approximately 10 years.
Aroldo P, de Carvalho, Eliane Mara Cesário, Pereira   +1 more
openaire   +2 more sources

Analysis of Bordetella pertussis pertactin and pertussis toxin types from Queensland, Australia, 1999–2003

BMC Infectious Diseases, 2006
Background In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and ...
Slack Andrew T, Byrne Shane
doaj   +1 more source