Results 11 to 20 of about 7,666 (128)

Acellular Pertussis Vaccine Inhibits Bordetella pertussis Clearance from the Nasal Mucosa of Mice. [PDF]

Vaccines (Basel), 2020
Bordetella pertussis whole-cell vaccines (wP) caused a spectacular drop of global pertussis incidence, but since the replacement of wP with acellular pertussis vaccines (aP), pertussis has resurged in developed countries within 7 to 12 years of the ...
Holubová J, Staněk O, Brázdilová L, Mašín J, Bumba L, Gorringe AR, Alexander F, Šebo P.   +7 more
europepmc   +2 more sources

Intranasal acellular pertussis vaccine provides mucosal immunity and protects mice from Bordetella pertussis. [PDF]

NPJ Vaccines, 2019
Current acellular pertussis vaccines fall short of optimal protection against the human respiratory pathogen Bordetella pertussis resulting in increased incidence of a previously controlled vaccine- preventable disease.
Boehm DT, Wolf MA, Hall JM, Wong TY, Sen-Kilic E, Basinger HD, Dziadowicz SA, Gutierrez MP, Blackwood CB, Bradford SD, Begley KA, Witt WT, Varney ME, Barbier M, Damron FH.   +14 more
europepmc   +2 more sources

Pertussis post-exposure prophylaxis among household contacts: a cost-utility analysis. [PDF]

, 2015
BACKGROUND: Recent pertussis outbreaks have prompted re-examination of post-exposure prophylaxis (PEP) strategies, when immunization is not immediately protective.
Crowcroft, Natasha S, Crowcroft Natasha S., Sander Beate, Natasha S Crowcroft, Thampi, Nisha, Nisha Thampi, Gurol-Urganci Ipek, Thampi Nisha, Gurol-Urganci, Ipek, Beate Sander, Ipek Gurol-Urganci, Sander, Beate   +11 more
core   +1 more source

Comparative study of a whole-cell pertussis vaccine and a recombinant acellular pertussis vaccine.

, 1994
The safety and immunogenicity of an acellular pertussis vaccine containing the genetically detoxified pertussis toxin PT-9K/129G, filamentous hemagglutinin, and pertactin, together with diphtheria and tetanus toxoids, were compared with those of a whole ...
RAPPUOLI R. AND THE ITALIAN MULTICENTER GROUP FOR THE STUDY OF RECOMBINANT ACELLULAR PERTUSSIS VACCINE, PEPPOLONI, Samuele, MAIDA A., FURLAN R., UXA F., CARAPELLA DE LUCA E., NENCIONI L., CONTU B., TITONE L., MOIRAGHI A., STRAMARE D., DI PISA F., PODDA A.   +12 more
core   +2 more sources

Haemophilus influenzae type b reemergence after combination immunization

, 2006
An increase in Haemophilus influenzae type b (Hib) in British children has been linked to the widespread use of a diphtheria/tetanus/acellular pertussis combination vaccine (DTaP-Hib).
Mary P.E. Slack, Heath, PT, Diane Irving, Slack, MPE, Nik G. Johnson, Lee, YC ; https://orcid.org/, Irving, D, Sheldon, J, Gail F. Balfour, Joanna Sheldon, Johnson, NG, Ruggeberg, JU, Balfour, GF, Slack, MP, Y. Chen Lee, Heath, PI, Pollard, AJ, Jens U. Ruggeberg, Paul T. Heath, Pollard, Andrew, Andrew J. Pollard, Lee, YC, Liddy, H, Helen Liddy   +23 more
core   +1 more source

An open-label randomized clinical trial of prophylactic paracetamol coadministered with 7-valent pneumococcal conjugate vaccine and hexavalent diphtheria toxoid, tetanus toxoid, 3-component acellular pertussis, hepatitis B, inactivated poliovirus, and Haemophilus influenzae type b vaccine

, 2013
BACKGROUND: In two clinical trials, low-grade fever was observed more frequently after coadministration than after separate administration of two recommended routine pediatric vaccines.
Rose, Markus A., William C Gruber, Sherryl Baker, Christine Juergens, Beate Schmoele-Thoma, Gruber, William C., Stefan Zielen, Zielen, Stefan, Jürgens, Christine, Schmoele-Thoma, Beate, Baker, Sherryl, Markus A Rose   +11 more
core   +1 more source

Purification design and practice for pertactin, the third component of acellular pertussis vaccine, from Bordetella pertussis

, 2016
Development of acellular pertussis vaccine (aPV) requires purification of several components from Bordetella pertussis. While the components pertussis toxin (PT) and filamentous hemagglutinin (FHA) have been successfully purified, the third component ...
Li, Zenglan, Zhang, Songping, Li, Zhengjun, Zhang, Guifeng, Wang, Qi, Zhang, Yan, Ma, Guanghui, Su, Zhiguo, Liu, Yongdong, Luo, Jian   +9 more
core   +1 more source

Bacterial outer membrane vesicles and vaccine applications

, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Jose Luis Perez, Sonsire Fernández, Fernandez, Sonsire, Daniel eCardoso, Armando Acosta, Rosenqvist, Einar, Armando eAcosta, Concepcion eCampa, Campa, Concepcion, Luis eGarcia, Daniel Cardoso, Cardoso, Daniel, Zayas, Caridad, Luis Garcia, Caridad eZayas, Concepcion Campa, Caridad Zayas, Acevedo, Reinaldo, Reinaldo eAcevedo, Sarmiento, Maria Elena, Garcia, Luis, Valerie A Ferro, Sonsire eFernandez, Ferro, Valerie, Einar Rosenqvist, Acosta, Armando, Reinaldo Acevedo, Perez, Jose Luis, Einar eRosenqvist, Valerie A. Ferro, Maria Elena Sarmiento   +30 more
core   +1 more source

Swedish Infants Developed Pertussis at a Younger Age if Their Mother Was the Possible Source of Infection in 2009–2015

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to investigate the possible source of laboratory‐confirmed pertussis in infants under 6 months of age. Methods This nationwide prospective study was based on laboratory‐confirmed cases reported in the enhanced pertussis surveillance in Sweden from 2009 to 2015. The parents or carers of 345 infants were interviewed
Bernice Aronsson, Lennart Nilsson, Jann Storsaeter, Henrik Källberg, Emma Appelqvist   +4 more
wiley   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source