Results 21 to 30 of about 53,895 (223)
Vaccines, 2021 The research and development of a pertussis-combined vaccine using a novel inactivated poliovirus vaccine made from the Sabin strain (sIPV) is of great significance in the polio eradication project and to address the recent resurge in pertussis.
Xiaoyu Wang +7 more
doaj +1 more source
Severe pertussis infection in infants less than 6 months of age: clinical manifestations and molecular characterization [PDF]
, 2017 We conducted a study to determine the main traits of pertussis among unimmunized infants less than 6 months of age. From August 2012 to March 2015, 141 nasopharyngeal aspirates (NPAs) were collected from infants with respiratory symptoms attending 2
Buttinelli, Gabriele +12 more
core +1 more source
Pregnancy has a minimal impact on the acute transcriptional signature to vaccination. [PDF]
, 2020 Vaccination in pregnancy is an effective tool to protect both the mother and infant; vaccines against influenza, pertussis and tetanus are currently recommended.
Aerssens, A +10 more
core +1 more source
Pediatric Infectious Disease Journal, 2009 A critical level of serum IgG pertussis toxin antibody is both essential and sufficient to confer individual and herd immunity to pertussis. Monocomponent pertussis toxoid conferred such immunity in Sweden and in Denmark. We refute the notion that filamentous hemagglutinin, pertactin, and fimbriae add to the immunity conferred by pertussis toxoid and ...
John B, Robbins +5 more
openaire +2 more sources
Bacterial outer membrane vesicles and vaccine applications [PDF]
, 2014 Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo +10 more
core +2 more sources
International Journal of Microbiology, 2020 Background. Bordetella pertussis is a human pathogen which causes pertussis, or whooping cough. The diphtheria-tetanus-pertussis immunization has significantly reduced the morbidity and mortality of pertussis globally.
Solomon Taye +3 more
doaj +1 more source
Pertussis Toxin: A Key Component in Pertussis Vaccines?
Toxins, 2019 B. pertussis is a human-specific pathogen and the causative agent of whooping cough. The ongoing resurgence in pertussis incidence in high income countries is likely due to faster waning of immunity and increased asymptomatic colonization in individuals ...
Kelsey A. Gregg, Tod J. Merkel
doaj +1 more source
Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells [PDF]
, 2017 Pertussis is a respiratory infection caused by Bordetella pertussis that may be particularly severe and even lethal in the first months of life when infants are still too young to be vaccinated. Adults and adolescents experience mild symptoms and are the
Carsetti, Rita +13 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2019 Pertussis is a respiratory infectious disease that has been resurged during the last decades. The change from the traditional multi-antigen whole-cell pertussis (wP) vaccines to acellular pertussis (aP) vaccines that consist of a few antigens formulated ...
María Eugenia Zurita +7 more
doaj +1 more source
Iranian Journal of Microbiology, 2020 Background and Objectives: There are many pertussis outbreaks which is mainly due to the reduction in the immunity of acellular pertussis (aP) vaccines. Therefore, there is a crucial necessity to develop a new generation of pertussis vaccine.
Mohammad Sekhavati +3 more
doaj +1 more source