Results 121 to 130 of about 756,186 (307)
Kassi helge kuju eesti rahvapärimuses [PDF]
The article opens with an overview about the extremely positive image of the cat in contemporary Estonian media, but also about the considerably more ambivalent image familiar from modern beliefs, truisms, narrative sequels, and comparisons. Some truisms
Kristi Salve
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Fluorodeoxyglucose PET in Neurology and Psychiatry
PET imaging with the most widely available PET tracer, 2-deoxy-2-[(18)F]fluoro-d-glucose (FDG), is a powerful tool in the differential diagnosis of numerous neurologic and psychiatric disorders, particularly in early disease stages.
Damian, A. +2 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FDG PET/CT vizsgálatok szerepe az ovarium carcinomák diagnosztikájában
Az ovarium carcinomák a legnagyobb mortalitással rendelkező nőgyógyászati daganatok. Ennek legfőbb oka, hogy az esetek döntő többségében már előrehaladott stádiumban kerülnek felismerésre.
Ónodi-Szücs, Gergő
core
On the management of a tropical reservoir fishery [PDF]
The major factor in the development of Sri Lankan inland fisheries was the introduction, in 1952, of the exotic cichlid Oreochromis mossambicus (Peters) which dominated the catch ever since.
Pet, J.S.
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Amyloid PET data analysis: Dorian and the central limits theorem
reservedLa malattia di Alzheimer è la demenza più comune nella popolazione di età superiore ai 65 anni; la formazione di placche di amiloide-beta è un fattore importante nella patogenesi del morbo di Alzheimer e inizia diversi anni prima della ...
COBO, ROLINDA
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source

