Results 1 to 10 of about 483,370 (134)

Feasibility of imaging synaptic density in the human spinal cord using [11C]UCB-J PET

open access: yesEJNMMI Physics, 2022
Purpose Neuronal damage and synapse loss in the spinal cord (SC) have been implicated in spinal cord injury (SCI) and neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS).
Samantha Rossano   +7 more
doaj   +1 more source

Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation

open access: yesEJNMMI Research, 2022
Highlights In a focal rat DTH-EAE model of neuroinflammation, dimethyl fumarate decreases the uptake of TSPO PET tracer [18F]GE-180 in the short term. Long-term [18F]GE-180 follow-up did not indicate a treatment effect.
S. K. Vainio   +10 more
doaj   +1 more source

ImmunoPET Directed to the Brain: A New Tool for Preclinical and Clinical Neuroscience

open access: yesBiomolecules, 2023
Immuno-positron emission tomography (immunoPET) is a non-invasive in vivo imaging method based on tracking and quantifying radiolabeled monoclonal antibodies (mAbs) and other related molecules, such as antibody fragments, nanobodies, or affibodies ...
Ángel García de Lucas   +2 more
doaj   +1 more source

Improved detection of molecular markers of atherosclerotic plaques using sub-millimeter PET imaging [PDF]

open access: yes, 2020
Since atherosclerotic plaques are small and sparse, their non-invasive detection via PET imaging requires both highly specific radiotracers as well as imaging systems with high sensitivity and resolution.
Bormans, Guy   +11 more
core   +2 more sources

Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand 11C-UCB-J

open access: yesEJNMMI Research, 2020
The ability to quantify synaptic density in vivo in human adults and adolescents is of vital importance to understanding neuropsychiatric disorders.
Jason Bini   +9 more
doaj   +1 more source

18F-PSMA-1007 PET/CT Performance on Risk Stratification Discrimination and Distant Metastases Prediction in Newly Diagnosed Prostate Cancer

open access: yesFrontiers in Oncology, 2021
ObjectiveTo evaluate the prediction performance of 18F-PSMA-1007 PET/CT and clinicopathologic characteristics on prostate cancer (PCa) risk stratification and distant metastatic prediction.Materials and MethodsA retrospective analysis was performed on ...
Zhuonan Wang   +7 more
doaj   +1 more source

Adaptive noise depression for functional brain network estimation

open access: yesFrontiers in Psychiatry, 2023
Autism spectrum disorder (ASD) is one common psychiatric illness that manifests in neurological and developmental disorders, which can last throughout a person's life and cause challenges in social interaction, communication, and behavior.
Di Ma, Di Ma, Liling Peng, Xin Gao
doaj   +1 more source

The value of 18F-PSMA-1007 PET/CT in identifying non-metastatic high-risk prostate cancer

open access: yesEJNMMI Research, 2020
Background Clinical management decisions on prostate cancer (PCa) are often based on a determination of risk. 68Ga-prostate-specific membrane antigen (PSMA)-11-positron emission tomography (PET)/computer tomography (CT) is an attractive modality to ...
Jun-jie Hong   +7 more
doaj   +1 more source

[18F]Fluoride uptake in various bone types and soft tissues in rat

open access: yesEJNMMI Research, 2023
Background In the development of new 18F-labelled tracers, it is important to assess the amount of released [18F]fluoride taken up in the bones of experimental animals because all 18F-labelled PET-tracers are prone, to lesser or higher degree, to undergo
Nina Savisto   +8 more
doaj   +1 more source

The Integration of Positron Emission Tomography With Magnetic Resonance Imaging [PDF]

open access: yes, 2008
A number of laboratories and companies are currently exploring the development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET).
Cherry, Simon R.   +2 more
core   +1 more source

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