Results 131 to 140 of about 307,140 (314)

Detectability of colorectal neoplasia with fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (FDG-PET/CT)

, 2011
The purpose of this study was to analyze the detectability of colorectal neoplasia with fluorine-18-2-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT). Data for a total of 492 patients who had undergone both PET/CT
Saito, Shunsuke, Sakiko Hiraoka, Tomoko Hirakawa, Kato, Jun, Shunsuke Saito, Hirakawa, Tomoko, Kaji, Eisuke, Higashi, Reiji, Sakuma Takahashi, Mitsuhiro Akita, Hori, Keisuke, Yoshihiro Okumura, Toshio Uraoka, Akita, Mitsuhiro, Kazuhide Yamamoto, Okumura, Yoshihiro, Hiraoka, Sakiko, Jun Kato, Reiji Higashi, Takahashi, Sakuma, Yamamoto, Kazuhide, Eisuke Kaji, Uraoka, Toshio, Keisuke Hori, Suzuki, Hideyuki, Hideyuki Suzuki   +25 more
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

A Study of 3-Substituted 7-Methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ols Leading to Candidate PET Radioligands for Imaging Brain GluN2B: Design, Synthesis, and Structure–Activity Relationships

Molecules
N-Methyl-D-aspartate (NMDA) receptors are ligand- and voltage-gated ion channels essential for synaptic plasticity, learning, and memory. The GluN2B subunit, highly expressed in the forebrain and spinal cord, is implicated in multiple neurological and ...
Lisheng Cai, Leah Noelle Millard, Sean Wallace Costner, Alyssa Wang, Yonglan Liu, Victor William Pike   +5 more
doaj   +1 more source

PET myocardial perfusion quantification: anatomy of a spreading functional technique [PDF]

Purpose To summarize the physical principles, imaging method, available tools for and the clinical value of quantitative perfusion evaluation with cardiac PET as well as future aims in the field in a narrative review.Results Cardiac positron-emission ...
Knuuti J, Walls-Laguarda L, Casares-Echeverria LJ, Alexanderson E, Cruz-Mendoza JR, Guinto-Nishimura GY, Juarez-Orozco LE, Meave-Gonzalez A   +7 more
core   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Diagnostic Performance of Quantitative Perfusion Cardiac Magnetic Resonance Imaging in Patients with Prior Coronary Artery Disease [PDF]

Aims: The diagnostic performance of quantitative perfusion cardiac magnetic resonance (QP-CMR) imaging has scarcely been evaluated in patients with a history of coronary artery disease (CAD) and new onset chest pain.
van Diemen, PA, Götte, MJW, von Bartheld, MB, Underwood, SR, Danad, I, Somsen, YBO, J, Maaniitty, Nagel, E, Robbers, LFHJ, Twisk, JWR, Borodzicz-Jazdzyk, S, T, de Winter, RW, Knuuti, Hoek, R, Demirkiran, A, Jukema, RA, Raijmakers, PG, Knaapen, P, Driessen, RS   +20 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

F‐fluorodeoxyglucose PET and MR imaging

, 2010
Purpose: To compare 11C-choline positron emission tomography (C-PET), 18F-fluorodeoxyglucose PET (FDG-PET), and MR imaging in the preoperative detection of prostate cancer.
Yamamoto, Naoki, Yamada, Toru, Kyongtae T. Bae, Hiroaki Hoshi, Naoki Yamamoto, Toru Yamada, Satoshi Goshima, Watanabe, Haruo, Kondo, Hiroshi, Kako, Nobuo, Kanematsu, Masayuki, Bae, Kyongtae T., Haruo Watanabe, Nobuo Kako, Hoshi, Hiroaki, Hiroshi Kondo, Goshima, Satoshi, Masayuki Kanematsu   +17 more
core   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source