Results 41 to 50 of about 528,168 (327)

Feasibility of positron range correction in 82-Rubidium cardiac PET/CT

EJNMMI Physics, 2022
Background Myocardial perfusion imaging (MPI) using positron emission tomography (PET) tracers is an essential tool in investigating diseases and treatment responses in cardiology.
Malte Jensen, Simon Bentsen, Andreas Clemmensen, Jacob Kildevang Jensen, Johanne Madsen, Jonas Rossing, Anna Laier, Philip Hasbak, Andreas Kjaer, Rasmus Sejersten Ripa   +9 more
doaj   +1 more source

GePEToS : A Geant4 Monte Carlo simulation package for Positron Emission Tomography [PDF]

, 2003
GePEToS is a simulation framework developed over the last few years for assessing the instrumental performance of future PET scanners. It is based on Geant4, written in Object-Oriented C++ and runs on Linux platforms.
Collot, J., Gallin-Martel, M. -L., Jan, S., Martin, P., Mayet, F., Tournefier, E.   +5 more
core   +3 more sources

The Search for a Subtype-Selective PET Imaging Agent for the GABA Receptor Complex: Evaluation of the Radiotracer [C]ADO in Nonhuman Primates

Molecular Imaging, 2017
The myriad physiological functions of γ-amino butyric acid (GABA) are mediated by the GABA-benzodiazepine receptor complex comprising of the GABA A , GABA B , and GABA C groups.
Shu-fei Lin PhD, Frederic Bois PhD, Daniel Holden BA, Nabeel Nabulsi PhD, Richard Pracitto MS, Hong Gao MS, Michael Kapinos BS, Jo-ku Teng BS, Anupama Shirali PhD, Jim Ropchan PhD, Richard E. Carson PhD, Charles S. Elmore PhD, Neil Vasdev PhD, Yiyun Huang PhD   +13 more
doaj   +1 more source

Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation

EJNMMI Research, 2019
Background Positron emission tomography (PET) can be used for in vivo evaluation of the pathology associated with multiple sclerosis. We investigated the use of longitudinal PET imaging and the 18-kDa translocator protein (TSPO) binding radioligand [18F ...
S. K. Vainio, A. M. Dickens, J. Tuisku, O. Eskola, O. Solin, E. Löyttyniemi, D. C. Anthony, J. O. Rinne, L. Airas, M. Haaparanta-Solin   +9 more
doaj   +1 more source

Comparison of manual and semi-automated delineation of regions of interest for radioligand PET imaging analysis [PDF]

, 2007
BACKGROUND As imaging centers produce higher resolution research scans, the number of man-hours required to process regional data has become a major concern. Comparison of automated vs.
Black, Sandra, Caldwell, Curtis B, Chow, Tiffany W, Honjo, Kie, Kusano, Maggie L, Pataky, Christina E, Ramirez, Joel, St Jacques, Peggy L, Takeshita, Shinichiro, Verhoeff, Nicolaas P L G   +9 more
core   +2 more sources

Data-driven analysis of kappa opioid receptor binding in major depressive disorder measured by positron emission tomography

Translational Psychiatry, 2021
Preclinical studies have implicated kappa opioid receptors (KORs) in stress responses and depression-related behaviors, but evidence from human studies is limited.
Kelly Smart, Ashley Yttredahl, Maria A. Oquendo, J. John Mann, Ansel T. Hillmer, Richard E. Carson, Jeffrey M. Miller   +6 more
doaj   +1 more source

Clinical translation of [18F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer [PDF]

, 2018
Background: Effective anticancer therapy is thought to involve induction of tumour cell death through apoptosis and/or necrosis. [18F]ICMT-11, an isatin sulfonamide caspase-3/7-specific radiotracer, has been developed for PET imaging and shown to have ...
Aboagye, Eric O., Cleator, S., Coombes, R. C., Dubash, S. R., Heinzmann, K., Inglese, M., Kenny, Laura, Kozlowski, K., Lavdas, I., Lewanski, C., Lim, A. K., Masrour, N., Mauri, F., Merchant, S., Rama, N., Steel, J. F., Thornton, A.   +16 more
core   +1 more source

Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA

EJNMMI Research
Background P2X7 receptor has emerged as a potentially superior PET imaging marker to TSPO, the gold standard for imaging glial reactivity. [11C]SMW139 is the most recently developed radiotracer to image P2X7 receptor.
Obada M. Alzghool, Richard Aarnio, Jatta S. Helin, Saara Wahlroos, Thomas Keller, Markus Matilainen, Junel Solis, Jonathan J. Danon, Michael Kassiou, Anniina Snellman, Olof Solin, Juha O. Rinne, Merja Haaparanta-Solin   +12 more
doaj   +1 more source

Stability evaluation of [18F]FDG: literature study, stability studies from two different PET centres and future recommendations

EJNMMI Radiopharmacy and Chemistry, 2022
Background The need for a stability evaluation of [18F]FDG is evident. The main purpose of this study was to make recommendations for determining the shelf life based on the available stability literature and our own two-centre stability studies. Results
Jes G. Holler, Børge Renmælmo, Richard Fjellaksel   +2 more
doaj   +1 more source

Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions [PDF]

, 2015
The commercial availability of combined magnetic resonance imaging (MRI)/positron emission tomography (PET) scanners for clinical use has increased demand for easily prepared agents which offer signal or contrast in both modalities.
Al-Yassiry, M.M., Al-Yassiry, Mustafa M., Archibald, S.J., Archibald, Stephen J., Baghdadi, N., Baghdadi, Neazar, Burke, B.P., Burke, Benjamin P., Cawthorne, Christopher, Clemente, G.S., Clemente, Goncalo S., Clemente, Gonçalo S., Domarkas, Juozas, Gibbs, P., Gibbs, Peter, Kownacka, Alicja E., Lorch, Mark, Nigam, S., Nigam, Shubhanchi, Pickles, M., Pickles, Martin, Tripier, R., Tripier, Raphael, Tripier, Raphaël   +23 more
core   +2 more sources