ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou +6 more
wiley +1 more source
Synergistic effect of the next generation insecticide flupyradifurone with a fungal pathogen in the ant Lasius niger. [PDF]
Schläppi D +5 more
europepmc +1 more source
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai +7 more
wiley +1 more source
Broadening the Clinical Spectrum of Axonal Hereditary Neuropathies: A Comparative Case Study on DNAJB2- and HINT1-Related Disease. [PDF]
Bjelica B +8 more
europepmc +1 more source
3D Hydrogel Cell Cultures and Their Biomedical Applications
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai +7 more
wiley +1 more source
A Reliable In Planta Inoculation and Antifungal Screening Protocol for <i>Rhizoctonia solani</i>-Induced Sheath Blight in Rice. [PDF]
Yasin A +9 more
europepmc +1 more source
Migration and Dispersion Evolution of Exhaled Aerosol in a Ward Under Different Ventilation Modes
ABSTRACT Wards with special functions and closure will have a higher risk of viral transmission as aerosols are an important mode of transmission for the SARS‐CoV‐2 virus. In this study, an experimental platform was built to establish the relevant parameters of the aerosol model and the aerosol propagation model according to the experimental results ...
Jingzhi Zhang +8 more
wiley +1 more source
Effects of silver nanoparticle coating on peri-implant mucosa and microbiome. [PDF]
Ito R +5 more
europepmc +1 more source
Surfactant‐Enhanced Electrospun Nanofiber Filters for Efficient Viral and Bacterial Inactivation
In this work, electrospun polyacrylonitrile (PAN) nanofibrous filters functionalized with surfactants (CTAB, CPC, and SDS) were developed for air filtration applications. The PAN nanofiber mats enable efficient particulate matter capture while simultaneously providing antimicrobial and antiviral activity against bacteria (E. coli and S.
Edilton N. da Silva +9 more
wiley +1 more source
3D Flipwell Engineering for Developing Asynchronous Systems for Toxicologic and Immunomodulatory Therapies in Bacterial, Gut, and Immune Cells. [PDF]
Beamer MA, Furuta S.
europepmc +1 more source

