Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu +9 more
wiley +1 more source
Comparative volatilomics identifies ubiquitous sulfur compounds inhibiting the fungal pathogen <i>Rasamsonia argillacea</i>. [PDF]
Adam D +5 more
europepmc +1 more source
The Impact of oospores of Phytophthora infestans on late blight epidemics [PDF]
Flier, W.G. +3 more
core
Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu +12 more
wiley +1 more source
Using a 'one strain-many compounds' approach to screen a collection of diverse fungi from Aotearoa New Zealand for antibacterial activity against <i>Escherichia coli</i>. [PDF]
van de Pas S +8 more
europepmc +1 more source
Force stimulation promotes nerve regeneration by restoring cellular energy
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang +10 more
wiley +1 more source
The metabolite ILA of <i>Akkermansia muciniphila</i> improves AP-related intestinal injury by targeting and inhibiting CASP3 activity. [PDF]
Li P +12 more
europepmc +1 more source
This study quantifies the effects of different soils found in the food processing environment on the efficiency of pulsed‐xenon UV disinfection. Abstract Listeria monocytogenes is a foodborne illness that poses a significant threat to human health in young, old, and immunocompromised persons and accordingly, prevention of Listeria contamination is of ...
Nazanin Yasoubi +2 more
wiley +1 more source
Molecular Studies of <i>TCF4</i> Gene and Correlation with Late-Onset Fuchs Endothelial Corneal Dystrophy in the Greek Population: A Novel Cost-Effective Diagnostic Algorithm. [PDF]
Petri N +7 more
europepmc +1 more source
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source

