Results 171 to 180 of about 4,712 (265)

A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip

open access: yesAdvanced Intelligent Discovery, EarlyView.
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang   +9 more
wiley   +1 more source

Sound‐Based Assembly of Magnetically Actuated Soft Robots Toward Enhanced Release of Extracellular Vesicles

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao   +5 more
wiley   +1 more source

Magnetic Field Control Using an Electromagnetic Actuation System with Combined Air‐Core and Metal‐Core Coils

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
An electromagnetic manipulation system enhances magnetic field strength in the Z‐direction for 3D control of microrobots and nanoparticles. Featuring eight metal‐core coils and two air‐core coils arranged hemispherically, it ensures unimpeded workspace access and integrates imaging tools.
Nader Latifi Gharamaleki   +4 more
wiley   +1 more source

Dynamic Obstacle Avoidance of Metamorphic Microrobots Using Concentric Sector Navigator

open access: yesAdvanced Intelligent Systems, EarlyView.
Metamorphic magnetic microrobots are navigated using a concentric sector navigator for dynamic obstacle avoidance in both microroller and swarm states. After microroller transport, citrate‐triggered dissolution releases nanoparticles that reassemble into a controllable swarm.
Zhaowen Su   +4 more
wiley   +1 more source

3D Closed‐Loop Navigation of Magnetic Microswimmers Using Vision‐Derived Depth Feedback

open access: yesAdvanced Intelligent Systems, EarlyView.
A planar magnetic microswimmer is navigated in three dimensions under a standard microscope. Image defocus supplies a real‐time depth cue, and model‐predictive control with A* planning steers the body on surfaces and in free swimming. Axial position is regulated by propulsion alone, without magnetic field gradients or extra cameras.
Yasin Cagatay Duygu   +2 more
wiley   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

open access: yesAngewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao   +8 more
wiley   +2 more sources

Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment

open access: yesAnnals of Neurology, EarlyView.
Objective The antisense oligonucleotide tofersen is the first disease‐modifying drug for SOD1‐related amyotrophic lateral sclerosis (ALS) and was approved because of its ability to reduce SOD1 protein and neurofilament levels. The effect of tofersen on SOD1 activity is unclear but of clinical relevance because homozygous SOD1 mutations, linked to ...
Katharina Goehring   +18 more
wiley   +1 more source

Home - About - Disclaimer - Privacy