Results 131 to 140 of about 70,933 (311)

Feline Responses to Increasing Inclusion of Natural Olive Extract in Liquid or Dry Palatant Formulations Applied to Kibble Diets

Pets
Olive extract (OE) has been used in human foods for its nutraceutical effects, making it a product of interest for pet food. However, OE’s effect on palatability has not been examined. The study objective was to evaluate the palatability of dry cat foods
Catherine Kokemuller, Ryan Guldenpfennig, Clare Hsu, Krysten Fries-Craft   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Effect of Wheat Dextrin Fiber on the Fecal Microbiome and Short-Chain Fatty Acid Concentrations in Dogs: Randomized, Single-Blinded, Parallel-Group Clinical Trial

Pets
The purpose of this study was to assess the practical implications of supplementing soluble fiber in the diet of dogs. Dogs with a history of managed or active chronic enteropathy were randomized to receive either wheat dextrin (fiber group) or ...
Marianne Pan, Chi-Hsuan Sung, Rachel Pilla, Jan S. Suchodolski, Stacie C. Summers   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A study of the transference between empathy towards companion animals and empathy towards humans in children [PDF]

, 2000
Plan AViolence in our society is a growing concern. There is evidence of increasing violent behavior in young children. Problems such as teasing and schoolyard bullying have turned into vicious attacks and even murder. Professionals and lay persons alike
Lind, Mary A.
core  

Quo Vadis: Is Corporatisation Reshaping Companion Animal Veterinary Care in Europe?

Pets
In recent years, the European companion animal veterinary care market has experienced significant growth, with 166 million households (50%) owning one or more of Europe’s 352 million companion animals.
Alice Diana, Damjan Mickov, Rens van Dobbenburgh, Wiebke Jansen, Susanna Sternberg Lewerin, Stephan Neumann, Mette Uldahl, Nancy De Briyne   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Endangered Przewalski’s Horse, Equus przewalskii, Cloned from Historically Cryopreserved Cells

Animals
Cloning from historically cryopreserved cells offers a potential means to restore lost genetic variation or increase the representation of particular lineages within bottlenecked species, provided such biobanked materials are archived for such genetic ...
Ben J. Novak, Oliver A. Ryder, Marlys L. Houck, Kelcey Walker, Lexie Russell, Blake Russell, Shawn Walker, Sanaz Sadeghieh Arenivas, Lauren Aston, Gregg Veneklasen, Jamie A. Ivy, Klaus-Peter Koepfli, Anna Rusnak, Jaroslav Simek, Anna Zhuk, Andrea S. Putnam, Ryan Phelan   +16 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source