, 2014 Turnover of damaged, dysfunctional, or excess organelles is critical to cellular homeostasis. We screened mutants disturbed in peroxisomal protein import, and found that a deficiency in the exportomer subunits Pex1, Pex6, and Pex15 results in enhanced ...
James M Nuttall (816424) +2 more
core +1 more source
Reevaluation of the role of Pex1 and dynamin-related proteins in peroxisome membrane biogenesis [PDF]
, 2015 A recent model for peroxisome biogenesis postulates that peroxisomes form de novo continuously in wild-type cells by heterotypic fusion of endoplasmic reticulum–derived vesicles containing distinct sets of peroxisomal membrane proteins.
Alison M. Motley +9 more
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Peroxisomes are membrane-bound organelles that house enzymes essential for specialized metabolic processes, including the β-oxidation of very long-chain fatty acids. Their biogenesis and maintenance rely on approximately 35 Pex proteins.
Ali, Bashir
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, 2014 Total RNA was extracted from fungal mycelium that was grown in complete medium for 48h and then transferred to minimal medium containing oleic acid or triolein for 24; PEX6 (peroxisomal biogenesis), MFP1 (fatty acid β-oxidation), PTH2 (acetyl-CoA ...
Mohammad Termizi bin Yusof (581077) +3 more
core +1 more source
A Novel Role of Peroxin Pex6: Suppression of Aging Defects in Mitochondria
, 2011 [[abstract]]Yeast cells become older with each division, but their daughters are born young. Mutational analysis shows that maintenance of this age asymmetry requires segregation of a complement of active mitochondria to daughters and that this process ...
Seo, J. G.; C. Y. Lai; M. V. Miceli; S. M. Jazwinski
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Molecular analysis and prenatal diagnosis of peroxisome biogenesis disorders (1) Genomic stucture and identification of 11 novel mutations of the PEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders (2) Prenatal diagnosis of peroxisome biogenesis disorders by means of immunofluorescence staining of cultured chorionic villous cells [PDF]
, 2000 博士論文 (Doctoral dissertation)(1) Genomic stucture and identification of 11 novel mutations of the PEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders(2) Prenatal diagnosis of peroxisome biogenesis disorders by means ...
397137, 張, 忠義
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, 2017 Catabolism of fatty acids stored in oil bodies is essential for Arabidopsis seed germination and seedling development. In plants, this β-oxidation occurs exclusively in peroxisomes, conserved organelles that are delimited by a single lipid bilayer ...
Gonzalez, Kim Lani
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Molecular analysis and prenatal diagnosis of peroxisome biogenesis disorders (1) Genomic stucture and identification of 11 novel mutations of the PEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders (2) Prenatal diagnosis of peroxisome biogenesis disorders by means of immunofluorescence staining of cultured chorionic villous cells [PDF]
博士論文 (Doctoral dissertation)(1) Genomic stucture and identification of 11 novel mutations of the PEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders(2) Prenatal diagnosis of peroxisome biogenesis disorders by means ...
張, 忠義
core +1 more source
Pex1 and Pex6 are Type-2 AAA+ ATPases required for the de novo biogenesis of peroxisomes. Mutations in Pex1 and Pex6 account for the majority of the most severe forms of peroxisome biogenesis disorders in humans.
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, 2006 L'Afrique est un continent vaste, hétéroclite, riche en ressources naturelles et humaines, mais qui se débat toujours dans de nombreux problèmes tels que les guerres, la pauvreté et les maladies.
Krazy, Hanane
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