Results 61 to 70 of about 1,386 (148)
Pex26-Pex6-Pex1 overlaps with the disease complex No. 335.
, 2013 This figure showed the Pex26-Pex6-Pex1 complex (surrounded by green line) which covered a benchmark disease complex (surrounded by red dash line) that consisted of proteins O43933 (PEX 1) and Q13608 (PEX 6).
Peng Yang (296696) +4 more
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2022 目的本研究通过第二代高通量测序（NGS）检测配对骨肉瘤转移灶和原发灶标本，分析骨肉瘤原发灶与转移灶的基因图谱差异，以期发现促进骨肉瘤发生和转移的相关分子及可能机制。方法12例转移患者的原发灶与转移病灶肿瘤组织样本，使用第二代高通量测序（NGS）进行检测，其中9对panel检测（678个基因）以及3对全外显子检测（WES），分析比较骨肉瘤原发灶与转移灶的基因图谱差异：基因拷贝数变异通过EXCAVATOR检测；DNA层面的融合突变通过Lumpy检测；RNA层面的融合突变通过Defuse + STAR ...
许明贤 +4 more
doaj
LUCID: An Integrative Approach for Target Discovery and dsRNA Design in Plant Fungal Pathogens
Plant Biotechnology Journal, Volume 24, Issue 6, Page 3597-3615, June 2026.LUCID: A computational pipeline for RNAi‐based biofungicide design. ABSTRACT Phytopathogenic fungi pose an escalating threat to global food security and ecosystem stability, as resistance and environmental concerns diminish the effectiveness of conventional fungicides.
Lucía Jiménez‐Castro +4 more
wiley +1 more source
Annals of Translational Medicine, 2019 Zellweger spectrum disorder (ZSD) is an autosomal recessive peroxisome biogenesis disorder (PBD) caused by bi-allelic mutations in any of the 13 PEX family genes.We reported a Chinese PBD-ZSD patient with compound heterozygous mutations of PEX6 detected by target sequencing and Sanger sequencing. The clinical materials were collected.
Hui-Ling, Yu +3 more
openaire +2 more sources
International Journal of Genomics, Volume 2026, Issue 1, 2026.Fertility and milk production in dairy cattle are economically significant traits, but they exhibit an unfavorable genetic correlation, making simultaneous improvement challenging. Identifying pleiotropic genes that influence both traits can provide valuable insights for genomic selection.
Heydar Ghiasi +4 more
wiley +1 more source
Aggregate, Volume 6, Issue 10, October 2025.This study presents a supramolecular nanocomplex assembled from a natural polyphenol and Cu(II) that enables cascade glutathione (GSH) depletion through synthesis inhibition, redox cycling, and Michael addition. The system induces dual cytoplasmic and mitochondrial ferroptosis in cisplatin‐resistant hepatocellular carcinoma (HCC), reverses drug ...
Yan Qin +6 more
wiley +1 more source
JIMD Reports, Volume 66, Issue 5, September 2025.ABSTRACT We report the case of an 11‐year‐old girl who developed hepatopulmonary syndrome (HPS) as a rare complication of Zellweger spectrum disorder and was successfully treated with liver transplantation. Our patient presented with neonatal sensorineural hearing loss.
Riya Mary Tharakan +2 more
wiley +1 more source
, 2017 Catabolism of fatty acids stored in oil bodies is essential for seed germination and seedling development in Arabidopsis. This fatty acid breakdown occurs in peroxisomes, organelles that sequester oxidative reactions.
Fleming, Wendell A. +6 more
core +1 more source
Strong cis-acting expression quantitative trait loci for the genes encoding SNHG5 and PEX6
Medicine, 2016 Expression of quantitative trait loci (eQTLs) for the genes located in human chromosome 6 were examined. Data on RNA expression in lymphoblastoid cells of 373 unrelated Europeans were used to identify eQTLs.Genome-wide analysis resulted in 24,447 nucleotide variants associated with gene expression (P
Lee, Jihyeon, Ryu, Jihye, Lee, Chaeyoung
openaire +2 more sources
Nomogram Based on A‐To‐I RNA Editing for Predicting Overall Survival in Patients With Breast Cancer
Journal of Cellular and Molecular Medicine, Volume 29, Issue 18, September 2025.ABSTRACT Adenosine‐to‐inosine RNA editing (ATIRE) is the most common type of RNA editing in higher eukaryotes. Many RNA editing events are associated with the occurrence and development of various tumours. Currently, several ATIRE sites have been used as predictors of cancer prognosis.
Yangyang Zhang +7 more
wiley +1 more source