Results 101 to 110 of about 22,023 (250)

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

open access: yesAdvanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang   +8 more
wiley   +1 more source

An exciting Approach to Theoretical Spectroscopy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno   +29 more
wiley   +1 more source

Autonomous High‐Throughput Characterization of Liquid‐Liquid Phase Behavior

open access: yesAdvanced Science, EarlyView.
This study introduces an automated dual modality platform, combining asymmetric capacitance deviation and multiangle turbidimetry, for high‐throughput characterization of liquid‐liquid phase behavior across chemically diverse fluid systems. The platform enables miscibility classification, resolution of phase separation kinetics and emulsion stability ...
Tarek Eid   +3 more
wiley   +1 more source

Thermoelectric PANI/TeNWs Fiber Based Microsensor for Passive Temperature and Active Chemical Sensing

open access: yesAdvanced Science, EarlyView.
Continuous wet‐spinning of PANI with TeNWs yields a multifunctional microfiber. Oriented TeNWs impose chain alignment and enhance π‐electron delocalization, boosting the Seebeck coefficient to 59.9 µV K−1 for passive temperature sensing (1 K detection limit), while achieving high pH sensitivity (59.25 mV pH−1) and rapid NH3 response (0.96 s).
Dongmei Xie   +10 more
wiley   +1 more source

Two‐Dimensional Layered Materials for Aqueous Zinc‐Ion Batteries: Multifunctional Roles and Mechanistic Insights

open access: yesAdvanced Science, EarlyView.
This overview summarizes versatile 2D layered materials for AZIB anodes, cathodes, separators and electrolytes, illustrating their dendrite/side reaction suppression mechanisms, and analyzes existing hurdles to propose scalable commercial research outlooks.
Shuge Dai   +7 more
wiley   +1 more source

Theretofore Highest Efficiency in Vacuum‐Deposited Organic Solar Cells Originating From Triarylamine‐Based Small‐Molecule Donors Containing Fused Heterocycle Units

open access: yesAdvanced Science, EarlyView.
Fused‐ring engineering unlocks record efficiency in vacuum‐deposited organic solar cells. By replacing linear π‐bridges with fused‐ring analogues in triarylamine‐based donors, we achieve enhanced molecular planarity, red‐shift optical absorption, minimize energy loss and optimized phase separation.
Yun‐Fei Li   +13 more
wiley   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

open access: yesAdvanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang   +19 more
wiley   +1 more source

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