Results 191 to 200 of about 21,382 (238)

On Generalized PF-Rings

On Generalized PF-Rings
openaire  

High Prevalence of SOD1 Pathogenic Variants in the UK Biobank: Implications for Early Intervention in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective SOD1 is the second most frequently mutated gene in European patients with amyotrophic lateral sclerosis (ALS). Given the recent authorization of SOD1‐targeted antisense oligonucleotides for SOD1‐ALS, prompt screening for SOD1 mutations in patients with ALS patients is highly recommended.
Delia Gagliardi, Chiara Villella, Matteo Zanovello, Virginia Iacobelli, Stefania Corti, Giacomo Pietro Comi, Pietro Fratta, Henry Houlden, Arianna Tucci, Dario Ronchi   +9 more
wiley   +1 more source

Correlations Between Osteocyte Lacuno‐Canalicular Network and Material Characteristics in Healthy and Mechanically Stimulated Murine Tibiae

Advanced NanoBiomed Research, EarlyView.
This article reveals how calcium content, mineral nanostructure, and lacuno‐canalicular network (LCN) organization interact to shape bone heterogeneity in mouse tibiae. Advanced multimodal imaging uncovers that mechanical loading promotes mature mineral structures even in low‐calcium regions, highlighting LCN‐driven mineralization and offering new ...
Victoria Schemenz, Maximilian Rummler, Alexander van Tol, Isabela Vitienes, Tobias Thiele, Markus A. Hartmann, Manfred Burghammer, Peter Fratzl, Richard Weinkamer, Bettina M. Willie, Wolfgang Wagermaier   +10 more
wiley   +1 more source

Protein‐Template Gold Nanoclusters Induce Differentiation and Modify the Functional Properties of Primary Astrocytes

Advanced NanoBiomed Research, EarlyView.
The incubation of primary astrocytes with fAuNCs‐BSA induces: (A) long‐term effects including fAuNCs‐BSA internalization, red cell fluorescence, differentiation, upregulation of Ca2+ signaling, Cl‐current, and cell volume regulation. B) Short‐term (200 ms) stimulation with UV LED light increases in Ca2+ signaling and inhibition of K+ current. Astrocyte
Roberta Fabbri, Karima Jeneh Perry, Emanuela Saracino, Chiara Lazzarini, Anna Mariano, Diletta Spennato, Maria Grazia Mola, Maria Grazia Raucci, Alessandro Kovtun, Marianna Barbalinardo, Giorgia Conte, Denis Gentili, Marco Caprini, Vincenzo Palermo, Roberto Zamboni, Luigi Ambrosio, Wolfgang Losert, Andrea Candini, Grazia Paola Nicchia, Raj K. Gupta, Valentina Benfenati, Shashi P. Karna   +21 more
wiley   +1 more source

Discovery of a potent covalent inhibitor that unusually distorts the catalytic dyad of SARS-CoV-2 main protease. [PDF]

J Virol
Wang J, Sang X, Zheng W, Chan JF-W, Zhou J, Xu Y, Han P, Feng Y, Fu L, Tsang JO-L, Yuan S, Ciechanover A, An J, Yuen K-Y, Qi J, Huang Z.   +15 more
europepmc   +1 more source

Plasmodium falciparum stomatin-like protein forms a putative complex with a metalloprotease in distinct mitochondrial loci. [PDF]

PLoS Pathog
Verhoef JMJ, Bekkering ET, Boshoven C, Hannon M, Evers F, Proellochs NI, Spruijt CG, Kooij TWA.   +7 more
europepmc   +1 more source

The <i>Plasmodium falciparum</i> RING Finger Protein <i>Pf</i>RNF1 Forms an Interaction Network with Regulators of Sexual Development. [PDF]

Int J Mol Sci
Farrukh A, Musa S, Distler U, Tenzer S, Pradel G, Ngwa CJ.   +5 more
europepmc   +1 more source

Understanding the HIV-CA protein and the ligands that bind at the N-terminal domain (NTD) - C-terminal domain (CTD) interface. [PDF]

RSC Med Chem
Lang S.
europepmc   +1 more source

R. Dual Bimodules and PF Rings

R. Dual Bimodules and PF Rings
openaire  

Schistosoma japonicum infection: clinical significance of ultrasound findings. [PDF]

Trans R Soc Trop Med Hyg
Richter J, Wu HW, Ning A, Jiz MA, Aniceto R, Friedman J, Neumayr A, Hatz C.   +7 more
europepmc   +1 more source