Results 181 to 190 of about 170,636 (309)

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

Pulsed Field Ablation Versus High-Power Short-Duration Ablation for Atrial Fibrillation-A Meta-Analysis of Reconstructed Time-to-Event Data. [PDF]

J Cardiovasc Dev Dis
Bregion PB, Passos FS, Schena S, Fazzini L, Kirov H, Rossi CS, Doenst T, Di Franco A, Caldonazo T.   +8 more
europepmc   +1 more source

Research on PFAS

Cosmetics have gradually become indispensable in daily life; however, their safety concerns are increasingly prominent. Among them, per- and polyfluoroalkyl substances (PFAS) contained in cosmetics may enter the human body and induce diverse health hazards, raising growing public concern regarding their potential risks.
openaire   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Pulsed-Field Ablation of Confluent Inferior Pulmonary Vein With Narrowing and a Low-Voltage Area: A Case Report. [PDF]

Cureus
Tanaka Y, Yamaki M, Mizuguchi Y, Igarashi Y.   +3 more
europepmc   +1 more source

The PFAS hotspot HBM network: development of a HBM PFAS guidance document for emerging PFAS hotspots, based on shared experiences across PFAS hotspots in EU

ISEE Conference Abstracts, 2022
Katleen De Brouwere, Ann Colles, Gudrun Koppen, Elly Den Hond, Lisbeth E. Knudsen, Maria Uhl   +5 more
openaire   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Adjunctive posterior wall ablation with a balloon-in-basket pulsed-field ablation catheter in atrial fibrillation: feasibility, safety, and insights into targeted lesion delivery from the VOLT CE Mark study. [PDF]

Europace
Gunawardene MA, Tilz R, Haqqani H, DeLurgio D, Healy S, Osca J, Kalman JM, McLellan A, Jesser E, Chierchia GB, Zhai E, Knecht S, Lakkireddy D, Sanders P.   +13 more
europepmc   +1 more source