PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Ablation Methods and Catheter Settings for Ventricular Tachycardia Ablation: A Bench to Bedside Review: Part 2. [PDF]
Niespialowska-Steuden M +5 more
europepmc +1 more source
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Different approaches to persistent and long-standing persistent atrial fibrillation ablation using pulsed field ablation: impact of procedural workflows on arrhythmia termination. [PDF]
Dello Russo A +16 more
europepmc +1 more source
Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin +2 more
wiley +1 more source
Development and Psychometric Evaluation of the Psychological First Aid Competence (PFAC) Scale for Emergency Responders: A Cross-Sectional, Sequential-Exploratory Mixed-Methods Study. [PDF]
Rajai N +3 more
europepmc +1 more source
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui +9 more
wiley +1 more source
Acute kidney injury is associated with decreased platelet function in domestic cats. [PDF]
Kornya MR, Blois SL, Abrams-Ogg ACG.
europepmc +1 more source

