Results 191 to 200 of about 10,658 (266)

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage‐Myofibroblast Transition

Advanced Science, EarlyView.
Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang, Guan‐Lin Guo, Xiao‐Hui Guan, Min Hu, Qi‐Ming Huang, Ding‐Wen Guo, Hao‐Cheng Gu, You‐Qiong Zhuo, Ning Li, Hong‐Bo Xin, Ke‐Yu Deng   +10 more
wiley   +1 more source

Vegetable Activated Charcoal for Human Consumption Reduces Selected PFAS Levels in a Bile Secretion Model: Cues on Its Possible Clinical Use. [PDF]

Chem Res Toxicol
Bonetto A, De Toni L, Di Nisio A, Pagnin L, Ferlin A, Marcomini A, Foresta C.   +6 more
europepmc   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Oceanographic regime and foraging behaviour structure compound-specific PFAS variability in arctic-atlantic guillemots. [PDF]

Environ Sci Ecotechnol
Shen R, Ebinghaus R, Vassão DG, Ratcliffe N, Larsen T.   +4 more
europepmc   +1 more source

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

Occurrence of PFAS in municipal drinking water: a participatory case study in London, UK.

Env Sci Adv
Richardson AK, Tien WH, O'Hern CIZ, Francis W, Dack S, Barron LP, Píel FB.   +6 more
europepmc   +1 more source

Designing biochars for improved sorptive removal of per- and polyfluoroalkyl substances. [PDF]

J Environ Qual
Zheng W, Huggett E, Circenis S, Mainali K, Sharma B.   +4 more
europepmc   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

Advanced Science, EarlyView.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li, Chun‐Hui Zhang, Yong Wang, Cheng‐Yuan Li, Da‐Rong Wen, Xi Xia, Liang Zhou, Wei‐Ping Qian, Qing‐Yuan Sun, Chang‐Zhong Li   +9 more
wiley   +1 more source

Volatile per- and polyfluoroalkyl substances (PFAS) and other semi-volatile organic chemicals in indoor air of fire stations: the influence of gear storage conditions.

Environ Sci Process Impacts
Stapleton HM, Herkert NJ, Hay D, Hoffman K, Ormond RB.   +4 more
europepmc   +1 more source

Associations between serum persistent organic pollutants and polycystic ovary syndrome risk: a case-control study with mediation analysis. [PDF]

Front Public Health
Zhao Z.
europepmc   +1 more source