Results 201 to 210 of about 31,589 (307)

Suspect Screening for PFAS in Groundwater with an Accessible LC-MS Workflow. [PDF]

ACS Omega
da Silva BF, Bruckner KN, Queiroz SCN, Bottoli CBG, Chorover J, Abrell L.   +5 more
europepmc   +1 more source

BLADE‐ON‐PETIOLE Genes Enable Genetic Bottleneck Mitigation Through Cross‐Species Repurposing of Floral Persistence Traits

Advanced Science, EarlyView.
This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao, Qianwen Lyu, Tinghao Zhang, Yupan Zou, Yue Xie, Dandan Yang, Cao Xu, Xiaozhen Huang   +7 more
wiley   +1 more source

Relationship between perfluoroalkyl substance exposure and immunoglobulin E among Korean adults from Korean National Environmental Health Survey cycle 4 (2018-2020): a cross-sectional study. [PDF]

Front Public Health
Kim D, Lee KJ, Lee JH, Lee I.
europepmc   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

Volatile per- and polyfluoroalkyl substances (PFAS) and other semi-volatile organic chemicals in indoor air of fire stations: the influence of gear storage conditions.

Environ Sci Process Impacts
Stapleton HM, Herkert NJ, Hay D, Hoffman K, Ormond RB.   +4 more
europepmc   +1 more source

Per- and polyfluoroalkyl substances and adolescent bone mineral density: assessing periods of susceptibility. [PDF]

J Endocr Soc
Buckley JP, Marquess KM, Braun JM, Calafat AM, Cecil KM, Chen A, Lanphear BP, Wasserman H, Xu Y, Yolton K, Kuiper JR.   +10 more
europepmc   +1 more source

KCNJ2 is Required for NLRP3 Inflammasome Activation That Drives Allergic Airway Inflammation and Remodeling

Advanced Science, EarlyView.
This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui, Shumei Wu, Yang Peng, Yiqi Liu, Li Che, Shiying Chen, Feng Zhang, Dajiang Qin, Shiyue Li, Pixin Ran, Wenguang Yin   +10 more
wiley   +1 more source

Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and incidence of asthma and wheeze in childhood: A register-based cohort study in Ronneby, Sweden. [PDF]

PLoS Med
Blomberg AJ, Nielsen C, Borgström Bolmsjö B, Bind MA, Hartman L, Saxne Jöud A.   +5 more
europepmc   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Impact of PFAS exposure on lipid metabolic pathways: mechanisms and implicatins in carcinogenesis. [PDF]

Front Toxicol
Ferguson EJ, Tessmann JW, Zaytseva YY.
europepmc   +1 more source