Results 91 to 100 of about 19,243 (241)

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

open access: yesHaemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini   +4 more
wiley   +1 more source

The perturbational finite difference (PFD) scheme of variational step of convection-diffusion equation

open access: yes, 2005
摄动有限差分(PFD)方法是构造高精度差分格式的一种新方法。变步长摄动有限差分方法是等步长摄动有限差分方法的发展和推广。对需要局部加密网格的计算问题,变步长PFD格式不需要对自变量进行数学变换,且和等步长PFD格式一样,具有如下的共同特点:从变步长一阶迎风格式出发,通过把非微商项(对流系数和源项)作变步长摄动展开,展开幂级数系数通过消去摄动格式修正微分方程的截断误差项求出,由此获得高精度变步长PFD格式。该格式在一、二和三维情况下分别仅使用三、五和七个基点,且具有迎风性 ...
高智, 李明军, 李桂波
core   +2 more sources

Real-world therapeutic performance of pirfenidone for connective tissue disease-associated interstitial lung diseases

open access: yesTherapeutic Advances in Respiratory Disease
Background: Pirfenidone (PFD) is commonly applied for antifibrotic treatment in patients with idiopathic pulmonary fibrosis but has rarely been studied in cases with connective tissue disease-associated interstitial lung diseases (CTD-ILDs).
Xueting Yuan   +16 more
doaj   +1 more source

Evaluation of risk factors for acute stroke using combined CTA and MR HR-VWI imaging

open access: yesFrontiers in Neurology
ObjectiveTo investigate the correlation between the changes of peripheral carotid fat density (PFD), the occurrence of acute cerebral ischemia events and the characteristics of different dangerous plaques.MethodsA retrospective analysis was performed on ...
Lin Chen   +5 more
doaj   +1 more source

Machine Learning Model for Predicting Postoperative Pain in Cases of Irreversible Pulpitis

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim Postoperative pain is a frequent clinical concern following endodontic treatment. This study aimed to develop and validate supervised machine learning models to predict the occurrence of postoperative pain in cases of irreversible pulpitis.
Pedro Felipe de Jesus Freitas   +9 more
wiley   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic   +3 more
wiley   +1 more source

Orofacial Myofunctional Therapy for Feeding and Swallowing in Children From Four to 12 Years: What Does the Evidence Show? A Systematic Review

open access: yesJournal of Oral Rehabilitation, EarlyView.
This systematic review evaluated the effectiveness of orofacial myofunctional therapy (OMT) for improving feeding and swallowing outcomes in children aged 4–12 years. Searches of four databases identified 17 studies, all reporting positive feeding and/or swallowing outcomes, including improved eating and swallowing skills, orofacial muscle function and
Danielle Carey   +6 more
wiley   +1 more source

Conjugates of a Photoactivated Rhodamine with Biopolymers for Cell Staining

open access: yesThe Scientific World Journal, 2014
Conjugates of the photoactivated rhodamine dyes with biopolymers (proteins, polysaccharides, and nucleic acids) are important tools for microscopic investigation of biological tissue. In this study, a precursor of the photoactivated fluorescent dye (PFD)
Sergei Yu. Zaitsev   +4 more
doaj   +1 more source

Development and Systematic Evaluation of a Low-Irritation PFD-AIS Formulation for Pulmonary-Targeted Therapy

open access: yes
Background: To overcome the gastrointestinal and hepatic toxicity of oral pirfenidone (PFD) in the treatment of idiopathic pulmonary fibrosis (IPF), this study systematically constructed a minimal-component, buffer-free pirfenidone aerosol inhalation ...
Yan, Yidong   +13 more
core   +1 more source

RT-PCR analysis of stimulated (TGF-β1) and suppressed (PFD) primary hTFs.

open access: yes, 2017
Cultures of hTFs were treated with TGF-β1 [10 ng/ml], PFD [10−3 mol/l] or the combination of both, TGF-β1 and PFD for 48 h under serum-free culture conditions. NC (expression level of respective gene in untreated cells, dotted line) was set to 1.
Marina Hovakimyan (504827)   +7 more
core   +1 more source

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