Integrated Engineering of CAR‐T Cells for Solid Tumours
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
Detection of Potentially Toxic Elements and Tolerant Native Fungi Presence in an Urban Stream in Argentina. [PDF]
Arias LL +4 more
europepmc +1 more source
Summary Background and objectives The relationship between atopic dermatitis (AD), weight, height, and body mass index (BMI) in children and adolescents and the impact of systemic treatments is controversial. We report the distribution of weight, height, and BMI in the German TREATkids cohort compared to a standardized German cohort (Kromeyer‐Hauschild)
Barbara Kind +17 more
wiley +1 more source
Accelerated Mucopermeation and Penetration of the Polypeptide Antibiotic Colistin via Ionic Complexation with Polyphosphazene Carriers. [PDF]
Stadler P +5 more
europepmc +1 more source
Cyclophosphamide is associated with long‐term treatment‐free remission in patients with pemphigus
Summary Background and objective Pemphigus treatment has seen significant advancements, yet long‐term remission remains a challenge. Comparative data on the long‐term effectiveness of available therapies are limited. We compared 10‐year relapse rates in pemphigus patients treated with azathioprine or cyclophosphamide plus high‐dose IV corticosteroids ...
Bettina Santler +5 more
wiley +1 more source
The Role of γ-Polyglutamic Acid, Superphosphate, and Smectite-Silica Clay Additives in Stabilizing Organic Matter, Reducing the Bioavailability of Heavy Metals, and Limiting the Ecotoxicity of Composts Made from Poultry Litter and Biochar. [PDF]
Gondek K +4 more
europepmc +1 more source
The 2016 BJA/PGA special issue: a selection of six educational reviews [PDF]
Hugh C. Hemmings +2 more
openalex +1 more source
S1 Guideline: Therapy of generalized pustular psoriasis
Summary The S1 guideline “Therapy of generalized pustular psoriasis (GPP)” is a German guideline developed in accordance with the criteria of the AWMF. The full version addresses clinical presentation, pathogenesis, diagnosis and differential diagnosis, comorbidities, and therapy.
Rotraut Mößner +17 more
wiley +1 more source

