Results 171 to 180 of about 122,171 (336)
Background and Purpose Nimodipine, an L‐type voltage‐gated calcium channel blocker, is an approved cerebral vasorelaxant. We hypothesized that nimodipine attenuates the pro‐inflammatory shift in microglial phenotypes. Here, we analysed the effects of nimodipine on morphological and functional microglial phenotypes as well as their transcriptomic ...
István Pesti+10 more
wiley +1 more source
MID-TRIMESTER MTP USING ENDOCERVICAL PGE2 GEL AND SERIAL INTRAMUSCULAR CARBOPROST [PDF]
Goyal Bk, Gurneesh Singh
openalex +1 more source
Exploring the Activation of the Keap1‐Nrf2‐ARE Pathway by PAHs in Children's Toys
Our study evaluated the skin sensitisation risk of polycyclic aromatic hydrocarbons (PAHs) in toys, revealing that B[k]F, B[b]F and chrysene are highly potent sensitizers. Synergistic effects in PAH mixtures underscore the need to consider combined exposures when assessing environmental risks to children.
Jonas Lauenstein+6 more
wiley +1 more source
PGE2 and the innate immune response
Resumen del trabajo presentado al 12th World Congress on Inflammation, Symposium 3: Disease Modification in Osteoarthritis: Myth or Reality?; celebrado en Boston (US) del 8 al 12 de agosto de 2015.
openaire +1 more source
Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases
Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei+5 more
wiley +1 more source
Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma [PDF]
Das, Sunit+9 more
core +3 more sources
Time-dependent effect of LPS on PGE2 and TNF-α production by rat glial brain culture: influence of COX and cytokine inhibitors [PDF]
D. Shemi, AbedN Azab, J. Kaplanski
openalex +1 more source
Mitonuclear Communication in Stem Cell Function
In this review, we highlight the critical functions of mitonuclear communication and its impact on mitochondrial proteostasis. Additionally, we examine how mitonuclear signalling influences stem cell function, offering new insights into cellular homeostasis, stem cell therapies, and the potential for lifespan extension.
Baozhou Peng, Yaning Wang, Hongbo Zhang
wiley +1 more source
Continuous-flow biosynthesis of prostaglandin E2 (PGE2).
Toro Nakahara+5 more
openalex +2 more sources