Results 1 to 10 of about 31,003,476 (304)

Harnessing diet to modulate inflammation and symptom progression in endometriosis [PDF]

open access: yesFrontiers in Nutrition
Endometriosis (EMS) is an estrogen-dependent inflammatory disease affecting 10% of reproductive-age women, with up to 50% experiencing infertility. As primary care providers (PCPs) are often the first point of care, understanding dietary factors that ...
Tyler Thompson   +3 more
doaj   +2 more sources

Gastroprotective effect of zafirlukast against indomethacin induced gastric ulcer in rats via PGE2 and anti-inflammatory pathways [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): To evaluate the gastroprotective potential of zafirlukast against indomethacin-induced gastric ulcers in rats.Materials and Methods: Thirty-two male Wistar rats were included in this study and randomly divided into 4 equal groups (n=8 ...
Munaf Aal-Aaboda   +3 more
doaj   +1 more source

Prostaglandin E Receptors [PDF]

open access: yesJournal of Biological Chemistry, 2007
Prostaglandin (PG) E(2) exerts its actions by acting on a group of G-protein-coupled receptors (GPCRs). There are four GPCRs responding to PGE(2) designated subtypes EP1, EP2, EP3, and EP4 and multiple splicing isoforms of the subtype EP3. The EP subtypes exhibit differences in signal transduction, tissue localization, and regulation of expression ...
Yukihiko, Sugimoto, Shuh, Narumiya
openaire   +2 more sources

The role of some lipids and their metabolites in programmed cell death (lipoapoptosis).

open access: yesActa Biomedica Scientifica, 2022
In recent years, the understanding of the mechanisms involved in the regulation of lipoapoptosis signaling pathways has expanded considerably. However, many mechanisms of apoptosis induction by lipids as well as molecules mediating intracellular and ...
N. A. Ishutina, I. A. Andrievskaya
doaj   +1 more source

Integrated analysis of COX-2 and iNOS derived inflammatory mediators in LPS-stimulated RAW macrophages pre-exposed to Echium plantagineum L. bee pollen extract. [PDF]

open access: yesPLoS ONE, 2013
Oxidative stress and inflammation play important roles in disease development. This study intended to evaluate the anti-inflammatory and antioxidant potential of Echium plantagineum L. bee pollen to support its claimed health beneficial effects.
Eduarda Moita   +8 more
doaj   +1 more source

Studies on kinins and prostaglandins [PDF]

open access: yes, 1968
KININS: 01. The isolation of bradykinin, a plasma kinin from ox blood. Biochem, J., (1961), 2JLj 60-65. (with D.F. Elliott & G . P, Lewis ) || 02. The structure of bradykinin. Biocheni, J.. (I960), 76, 16 P. (with D.F. Elliott & G.P. Lewis) ||
Horton, E. W.
core   +3 more sources

Structures of human prostaglandin F2α receptor reveal the mechanism of ligand and G protein selectivity

open access: yesNature Communications, 2023
Prostaglandins and their receptors regulate various physiological processes. Carboprost, an analog of prostaglandin F2α and an agonist for the prostaglandin F2-alpha receptor (FP receptor), is clinically used to treat postpartum hemorrhage (PPH). However,
Xiuqing Lv   +12 more
doaj   +1 more source

Combination therapy with butyrate and docosahexaenoic acid for keloid fibrogenesis: an in vitro study [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: Background: A single, effective therapeutic regimen for keloids has not been established yet, and the development of novel therapeutic approaches is expected.
Kazuhiro Torii   +5 more
doaj   +1 more source

Prostaglandin E Synthases in Zebrafish [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2005
Objective— Prostaglandin E synthases (PGESs) are being explored as antiinflammtory drug targets as alternatives to cyclooxygenase (COX)-2. Located downstream of the cyclooxygenases, PGESs catalyze PGE 2 formation, and deletion of microsomal (m)-PGES-1 abrogates inflammation ...
Pini, Barbara   +5 more
openaire   +2 more sources

Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. [PDF]

open access: yesPLoS ONE, 2012
The contribution of inflammation to the pathogenesis of tendinopathy and high prevalence of re-injury is not well established, although recent evidence suggests involvement of prostaglandins.
Stephanie Georgina Dakin   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy