Results 31 to 40 of about 74,807 (316)
, 1977 The major initial steps in the degradation of the prostaglandins are the oxidation of the secondary alcohol group at C-15 and the reduction of the Δ13 double bond (for a recent review, see 1).
Granström, E, Elisabeth Granström
core +1 more source
PLoS Biology, 2021 Intrauterine infection/inflammation (IUI) is a major contributor to preterm labor (PTL). However, IUI does not invariably cause PTL. We hypothesized that quantitative and qualitative differences in immune response exist in subjects with or without PTL ...
Monica Cappelletti +11 more
doaj +1 more source
Metabolism of prostaglandins E, A, and C in serum
Journal of Biological Chemistry, 1975 Three prostaglandin-metabolizing enzymes were detected in human serum. One enzyme was a dehydrase that converted prostaglandin E to prostaglandin A, the second was a prostaglandin A isomerase that converted prostaglandin A to prostaglandin C and the third was a prostaglandin C isomerase that converted prostaglandin C to prostaglandin B.
H, Polet, L, Levine
openaire +2 more sources
Beilstein Journal of Organic Chemistry, 2012 Chemical defense of the invasive red alga Gracilaria vermiculophylla has been studied and compared to that of the noninvasive but related Gracilaria chilensis. Both species rely on a wound-activated chemical defense that makes them less attractive to the
Martin Rempt +3 more
doaj +1 more source
Biosynthesis of Prostaglandins
, 1977 The conversion of arachidonic acid into PGE2 by homogenates of sheep vesicular glands was demonstrated in 1964 by two groups (1,2). Analogous formation of PGE1 and PGE2 from al1-cis 8,11,14-eicosatri-enoic acid and al1-cis 5,8,11,14,17-eicosapentaenoic ...
Granström, E, Elisabeth Granström
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Studies on kinins and prostaglandins [PDF]
, 1968 KININS: 01. The isolation of bradykinin, a plasma kinin from ox blood. Biochem, J., (1961), 2JLj 60-65. (with D.F. Elliott & G . P, Lewis ) || 02. The structure of bradykinin. Biocheni, J.. (I960), 76, 16 P. (with D.F. Elliott & G.P. Lewis) ||
Horton, E. W.
core
Radioimmunoassays of Prostaglandins and Thromboxanes
, 1977 Radioimmunoassay is based on a competition between labeled and unlabeled molecules of a certain compound for the binding sites on an antibody directed against the same compound.
Granström, E, Elisabeth Granström
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FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source